ArticleJournal of adolescent and young adult oncology2017
Racial Differences in 20-Year Cardiovascular Mortality Risk Among Childhood and Young Adult Cancer Survivors.
Article in Journal of adolescent and young adult oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Long-term cardiovascular risk in survivors of hematologic malignancies: a meta-analysis.BMC cancer · 2026Pooled it
- Disparities in Cardiovascular Disease-Related Outcomes Among Cancer Survivors in the United States: A Systematic Review of the Literature.Heart, lung & circulation · 2024Pooled it
- Racial Differences in the Prognosis and Survival of Cutaneous Melanoma From 1990 to 2020 in North America: A Systematic Review and Meta-Analysis.Journal of cutaneous medicine and surgeryPooled it
- Childhood cancer and future cardiometabolic health.npj metabolic health and disease · 2026Review
- Food insecurity, dietary quality, and cardiovascular risk among early childhood cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Development and refinement of the Cardiovascular Health Equity through Food (CHEF) intervention for childhood cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Social Risk Burden among US Cancer Survivors across Adulthood: Evidence from the 2022-2023 BRFSS.Cancer research communications · 2026Article
- Neighborhood factors associated with late effects among survivors of adolescent and young adult cancer.Journal of cancer survivorship : research and practice · 2025Article
- Greenspace and Survival Among Older Women With Breast Cancer: Regional Variations Within the U.S. SEER-Medicare-Linked Database.JACC. Advances · 2025Article
- Racial and Ethnic Disparities in Cardiotoxicity in Patients With Cancer Treated With Anthracyclines.Journal of the American Heart Association · 2025Article
- Associations Between Social Determinants of Health, Allostatic Load, and Anthracycline Cardiotoxicity in a Diverse Patient Population.Journal of the American Heart Association · 2025Article
- Poverty, race, ethnicity, and survival in pediatric nonmetastatic osteosarcoma: a Children's Oncology Group report.Journal of the National Cancer Institute · 2024Article
- Racial and Ethnic Disparities in Survival Among People With Second Primary Cancer in the US.JAMA network open · 2023Article
- Disparities in physical activity in adolescent and young adult cancer survivors.Journal of cancer survivorship : research and practice · 2023Article
- Disparities in the long-term survival of adolescent and young adult diffuse large B cell lymphoma survivors.Cancer epidemiology · 2021Article
- The Burden of Late Effects and Related Risk Factors in Adolescent and Young Adult Cancer Survivors: A Scoping Review.Cancers · 2021Article
- Impact of Race, Ethnicity, and Socioeconomic Status over Time on the Long-term Survival of Adolescent and Young Adult Hodgkin Lymphoma Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Genetic Variants Associated with Therapy-Related Cardiomyopathy among Childhood Cancer Survivors of African Ancestry.Cancer research · 2021Article
- Cardiovascular Family History Increases Risk for Late-Onset Adverse Cardiovascular Outcomes in Childhood Cancer Survivors: A St. Jude Lifetime Cohort Report.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Racial and Ethnic Disparities in Health Outcomes Among Long-Term Survivors of Childhood Cancer: A Scoping Review.Frontiers in public health · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWhether cardiovascular disease (CVD) risk differs according to race and cancer type among survivors of childhood or young adulthood cancers is unknown.
methodsData from the years 1973-2011 were analyzed using the Surveillance, Epidemiology, and End Results (SEER) registries. Cases were categorized by ICD-0-3/WHO 2008 Adolescent and Young Adult classification. CVD death was determined by ICD-10 codes for diseases of the heart, atherosclerosis, cerebrovascular diseases, or other diseases of the arteries. Cox proportional hazards models were fitted to evaluate the hazard ratio (HR) and 95% confidence intervals (CIs) for the effects of race on time-to-event outcomes.
resultsA total of 164,316 cases of childhood and young adult primary cancers were identified. There were 43,335 total and 1466 CVD deaths among Black and White survivors. Black survivors had higher risks of all-cause mortality (HR: 1.75, 95% CI: 1.70-1.7) and CVD mortality (HR: 2.13, 95% CI: 1.85-2.46) compared to White survivors. The increased risk of CVD for Black survivors compared to White survivors persisted at 5-years (HR: 2.38, 95% CI: 1.83-3.10), 10-years (HR: 2.59, 95% CI: 2.09-3.21), and 20-years (HR: 2.31, 95% CI: 1.95-2.74) postdiagnosis, and varied by cancer type, with the highest HRs for melanoma (HR: 8.16, 95% CI: 1.99-33.45) and thyroid cancer (HR: 3.43, 95% CI: 1.75-6.73).
conclusionsBlack survivors of childhood or young adulthood cancers have a higher risk of CVD mortality compared to Whites that varies by cancer type. Knowledge of at-risk populations is important to guide surveillance recommendations and behavioral interventions. Further study is needed to understand the etiology of racial differences in CVD mortality in this population.
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