Evidence map›Paper›PMID 28530003›Full record

ArticleOpen access journal of ophthalmology2016

The E368Q Mutant Allele of

G Senthil Kumar, K Dinesh Kumar, P J Minogue, V M Berthoud, R Kannan, E C Beyer, S T Santhiya

Open access · diamondAbstract read
PubMed Full text at PMC
In one paragraph

Article in Open access journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

G Senthil KumarDepartment of Genetics, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, India.
K Dinesh KumarDepartment of Genetics, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, India.
P J MinogueDepartment of Pediatrics, University of Chicago, USA.
V M BerthoudDepartment of Pediatrics, University of Chicago, USA.
R KannanAppasamy Krishna Hospital, Velachery, India.
E C BeyerDepartment of Pediatrics, University of Chicago, USA.
S T SanthiyaDepartment of Genetics, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, India.
University of Madras · IN

Funding

BIOLOGY OF LENS INTERCELLULAR COMMUNICATIONR01EY008368 · NEI · WASHINGTON UNIVERSITY · PI BEYER, ERIC C · 1995 to 2018
$7.1M
NEI NIH HHS R01 EY008368
6 · The paper itself

Abstract

purposeTo determine the basis of the autosomal dominant congenital cataracts in a three generation south Indian pedigree.

methodsThe proband and several family members underwent a complete ophthalmic examination. The coding regions of eight candidate genes (

resultsCongenital cataracts (with some variations in phenotype) segregated as an autosomal dominant trait within a three generation pedigree. Three affected individuals (proband, sibling and mother) showed a sequence variation in the candidate gene

conclusionsThe E368Q mutant allele of

Identifiers

PMID28530003
PMCPMC5438206
OpenAlexW2889537793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.