Evidence map›Paper›PMID 28530000›Full record

ArticleAnnals of clinical cytology and pathology2016

Capillary endothelia from two ADPKD patients are polyploidy.

Sarmed H Kathem, Wissam A AbouAlaiwi, Xiaolin Zi, Surya M Nauli

Open access · greenAbstract read
In one paragraph

Article in Annals of clinical cytology and pathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sarmed H KathemDepartment of Biomedical & Pharmaceutical Sciences, Chapman University, Irvine, CA.
Wissam A AbouAlaiwiDepartment of Pharmacology and Experimental Therapeutics, University of Toledo, Toledo, OH.
Xiaolin ZiDepartment of Urology, University of California at Irvine, Orange, CA.
Surya M NauliDepartment of Biomedical & Pharmaceutical Sciences, Chapman University, Irvine, CA.
Chapman University · USUniversity of California, Irvine · USUniversity of Toledo · US

Funding

The roles of primary cilia in cardiovascular systemR01DK080640 · NIDDK · UNIVERSITY OF TOLEDO · PI NAULI, SURYA · 2008 to 2012
$1.6M
NIDDK NIH HHS R01 DK080640
6 · The paper itself

Abstract

Bilateral renal cyst formation is the main feature of autosomal dominant polycystic kidney disease (ADPKD). We and other laboratories have previously shown that cyst-lining epithelia of kidneys from ADPKD patients are characterized by polyploidy. In this report, we show that endothelia from the renal capillary beds of two ADPKD patients are also polyploidy. Spectral karyotyping study further confirms our flow cytometry analyses. We suggest that polyploidy may be used as a potential cellular marker in ADPKD.

Identifiers

PMID28530000
PMCPMC5436797
OpenAlexW2623178050

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.