Evidence map›Paper›PMID 28529959›Full record

ReviewJournal of immunology research2017

Getting "Inside" Type I IFNs: Type I IFNs in Intracellular Bacterial Infections.

Deann T Snyder, Jodi F Hedges, Mark A Jutila

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Bioluminescent imaging to investigateInfection and immunity · 2025
    Article
  6. The immune response toFrontiers in microbiology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Spotted Fever GroupMicrobiology spectrum · 2021
    Article
  16. Recent Advances on the Innate Immune Response toFrontiers in cellular and infection microbiology · 2021
    Review
  17. Article
  18. Interferons: Tug of War Between Bacteria and Their Host.Frontiers in cellular and infection microbiology · 2021
    Review
  19. Article
  20. AFrontiers in pediatrics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Deann T SnyderDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.
Jodi F HedgesDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.ORCID 0000-0002-7461-3972
Mark A JutilaDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.
Montana State University · US

Funding

VIRUSES: FROM PARTICLES TO PROTEOMICSP20RR020185 · NCRR · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2004 to 2011
$17.0M
Role of type I IFN and human TLR4 in Coxiella burnetii pathogenesisR21AI117441 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2016 to 2017
$396k
NCRR NIH HHS P20 RR020185NIAID NIH HHS R21 AI117441
6 · The paper itself

Abstract

Type I interferons represent a unique and complex group of cytokines, serving many purposes during innate and adaptive immunity. Discovered in the context of viral infections, type I IFNs are now known to have myriad effects in infectious and autoimmune disease settings. Type I IFN signaling during bacterial infections is dependent on many factors including whether the infecting bacterium is intracellular or extracellular, as different signaling pathways are activated. As such, the repercussions of type I IFN induction can positively or negatively impact the disease outcome. This review focuses on type I IFN induction and downstream consequences during infection with the following intracellular bacteria:

Indexed as

AnimalsBacterial InfectionsCytoplasmHumansInterferon Type IListeria monocytogenesListeriosisMacrophagesMiceSalmonella typhimuriumSignal TransductionInterferon Type I

Identifiers

PMID28529959
PMCPMC5424489
OpenAlexW2609981821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.