Evidence map›Paper›PMID 28529921›Full record

ArticleCardiovascular diagnosis and therapy2017

Mediterranean lifestyle and cardiovascular disease prevention.

Ekavi N Georgousopoulou, Duane D Mellor, Nenad Naumovski, Evangelos Polychronopoulos, Stefanos Tyrovolas, Suzanne Piscopo, Giuseppe Valacchi, Foteini Anastasiou, Akis Zeimbekis, Vassiliki Bountziouka and 10 more

Abstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Article
  9. Mediterranean Lifestyle: More Than a Diet, A Way of Living (and Thriving).Endocrine, metabolic & immune disorders drug targets · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Ekavi N GeorgousopoulouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Duane D MellorDepartment of Nutrition-Dietetics, University of Canberra, Faculty of Health, Canberra, Australia.
Nenad NaumovskiDepartment of Nutrition-Dietetics, University of Canberra, Faculty of Health, Canberra, Australia.
Evangelos PolychronopoulosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Stefanos TyrovolasDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Suzanne PiscopoDepartment of Health, University of Malta, Nutrition, Family and Consumer Studies Office, Msida, Republic of Malta.
Giuseppe ValacchiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Foteini AnastasiouClinic of Social and Family Medicine, School of Medicine, University of Crete, Heraklion, Greece.
Akis ZeimbekisHealth Center of Kalloni, General Hospital of Mitilini, Mitilini, Greece.
Vassiliki BountzioukaDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Efthimios GotsisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
George MetallinosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Dimitra TyrovolaDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Alexandra FoscolouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Josep-Antoni TurResearch Group on Community Nutrition and Oxidative Stress, Universitat de les Illes Balears & CIBERobn, E-07122 Palma de Mallorca, Spain.
Antonia-Leda MatalasDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Christos LionisClinic of Social and Family Medicine, School of Medicine, University of Crete, Heraklion, Greece.
Labros SidossisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Demosthenes PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
MEDIS study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to a Mediterranean dietary pattern is a well-established protective factor against cardiovascular disease (CVD). However, diet quality is only one aspect of the overall healthy lifestyle adopted by Mediterranean populations. The latter has never been evaluated as a multi-factorial composite lifestyle. Thus, the aim of the present study was to provide a broader picture of the Mediterranean lifestyle and its effects on CVD risk, among elderly individuals.

methodsDuring 2005-2015, 2,749 older (aged 65-100 years) from 21 Mediterranean islands (MEDIS) and the rural Mani region (Peloponnesus) of Greece were voluntarily enrolled onto the study. Dietary habits, physical activity status, socio-demographic characteristics, lifestyle parameters (sleep, smoking habits, social life and educational status) and clinical profile aspects were derived through standard procedures.

resultsThe overall prevalence of the traditional CVD risk factors were 62.3% for hypertension, 22.3% for diabetes mellitus (type 2) and 47.7% for hypercholesterolemia. The presence of diabetes mellitus was positively predicted by the geriatric depression scale (GDS) [odds ratio (OR) =1.13, 95% confidence interval (CI): 1.02-1.25] and by an urban residential environment (OR =2.57, 95% CI: 1.10-6.06) after adjusting for several confounders. Presence of hypertension was predicted by increasing age (OR =1.07, 95% CI: 1.02-1.12), increasing body mass index (BMI) (OR =1.12, 95% CI: 1.04-1.21), the habit of midday sleep (OR =2.07, 95% CI: 1.07-4.02) and inversely predicted by the frequency of socializing with friends (OR =0.767, 95% CI: 0.616-0.955). The estimated score in the GDS was the only independent positive predictor for the presence of hypercholesterolemia (OR =1.10, 95% CI: 1.01-1.21).

conclusionsLifestyle parameters such as social life, midday sleep (siesta) and residential environment are strongly associated with the presence of CVD risk factors in elderly and should be part of broader CVD prevention strategies to reduce the burden of the disease.

Indexed as

cardiovascular disease (CVD)elderlyMediterranean lifestyleprevention

Identifiers

PMID28529921
PMCPMC5418209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.