Evidence map›Paper›PMID 28529556›Full record

ArticleOncology letters2017

MicroRNA-326 suppresses the proliferation, migration and invasion of cervical cancer cells by targeting ELK1.

Ping Zhang, Feng Kong, Xinchao Deng, Yunhai Yu, Congzhe Hou, Tingting Liang, Lin Zhu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  7. A Review of miR-326 and Female Related Diseases.Acta histochemica et cytochemica · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ping ZhangDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Feng KongCentral Laboratory, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Xinchao DengDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Yunhai YuDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Congzhe HouDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Tingting LiangDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Lin ZhuDepartment of Gynecology, The Second Hospital of Shandong University, Jinan, Shandong 250033, P.R. China.
Second Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although microRNAs (miRNAs or miRs) are able to function as oncogenes or tumor suppressors, the role of miR-326 in regulating human cervical cancer cells remains unclear. In the present study, the expression of miR-326 was identified to be downregulated in cervical cancer cell lines and primary tumor samples, and the overexpression of miR-326 decreased cell proliferation, migration and invasion in cervical cell lines. Bioinformatics prediction and experimental validation results revealed that the function of miR-326 was achieved by targeting and repressing ETS domain-containing protein Elk-1 (

Indexed as

cervical cancerETS domain-containing protein Elk-1microRNA-326

Identifiers

PMID28529556
PMCPMC5431565
OpenAlexW2595699959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.