ReviewInfectious agents and cancer2017
The potential role of infectious agents and pelvic inflammatory disease in ovarian carcinogenesis.
Review in Infectious agents and cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- The global detection rate of human papillomavirus DNA in ovarian cancer: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Inducing factors and complication risks of pelvic inflammatory disease: a review.Frontiers in endocrinology · 2026Review
- Gynecological Cancer Oncobiome Systematic Review.Cancers · 2025Review
- Appraisal of the causal effect ofmedRxiv : the preprint server for health sciences · 2024Article
- The Oncobiome in Gastroenteric and Genitourinary Cancers.International journal of molecular sciences · 2022Review
- Cancer-inducing niche: the force of chronic inflammation.British journal of cancer · 2022Review
- Clinical analysis and artificial intelligence survival prediction of serous ovarian cancer based on preoperative circulating leukocytes.Journal of ovarian research · 2022Article
- How prevalent are symptoms and risk factors of pelvic inflammatory disease in a sexually conservative population.Reproductive health · 2021Article
- Review
- Detection of human cytomegalovirus in patients with epithelial ovarian cancer and its impacts on survival.Infectious agents and cancer · 2020Article
- Detection and genotyping of CMV and HPV in tumors and fallopian tubes from epithelial ovarian cancer patients.Scientific reports · 2019Article
- Antibodies Against Chlamydia trachomatis and Ovarian Cancer Risk in Two Independent Populations.Journal of the National Cancer Institute · 2019Article
- The Risk of Gynecologic and Urinary Tract Cancer with Pelvic Inflammatory Disease: A Population-Based Cohort Study.Journal of Cancer · 2019Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis.
aimTo review the literature on studies examining the association between ovarian cancer and bacterial or viral infection or pelvic inflammatory disease.
methodsDatabase search through MEDLINE, applying the medical subject headings: "Ovarian neoplasms", AND "Chlamydia infections", "
resultsSeven studies examined the association between bacterial infection and ovarian cancer. A single study found a significant association between chlamydial infection and ovarian cancer, while another study identified
conclusionsData indicate a potential association between pelvic inflammatory disease and ovarian cancer. An association between ovarian cancer and high-risk human papillomavirus genotypes may exist in Asia, whereas an association in Western countries seems unlikely due to the low reported prevalence. Potential carcinogenic bacteria were found, but results were inconsistent, and further research is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.