ArticleDose-response : a publication of International Hormesis Society
Radiotherapy for Pertussis: An Historical Assessment.
Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Could pulmonary low-dose radiation therapy be an alternative treatment for patients with COVID-19 pneumonia? Preliminary results of a multicenter SEOR-GICOR nonrandomized prospective trial (IPACOVID trial).Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Trial
- Effect of Low-Dose Radiotherapy on the Circulating Levels of Paraoxonase-1-Related Variables and Markers of Inflammation in Patients with COVID-19 Pneumonia.Antioxidants (Basel, Switzerland) · 2022Article
- Review
- Low dose radiation therapy as a potential life saving treatment for COVID-19-induced acute respiratory distress syndrome (ARDS).Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2020Review
- Death of the ALARA Radiation Protection Principle as Used in the Medical Sector.Dose-response : a publication of International Hormesis SocietyArticle
- Necrotizing Fasciitis: Low-Dose Radiotherapy as a Potential Adjunct Treatment.Dose-response : a publication of International Hormesis SocietyReview
- X-Ray Hesitancy: Patients' Radiophobic Concerns Over Medical X-rays.Dose-response : a publication of International Hormesis SocietyArticle
- Immunomodulation Through Low-Dose Radiation for Severe COVID-19: Lessons From the Past and New Developments.Dose-response : a publication of International Hormesis SocietyReview
- Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement.Dose-response : a publication of International Hormesis SocietyArticle
- Radiophobic Fear-Mongering, Misappropriation of Medical References and Dismissing Relevant Data Forms the False Stance for Advocating Against the Use of Routine and Repeat Radiography in Chiropractic and Manual Therapy.Dose-response : a publication of International Hormesis SocietyArticle
- Radiophobia Overreaction: College of Chiropractors of British Columbia Revoke Full X-Ray Rights Based on Flawed Study and Radiation Fear-Mongering.Dose-response : a publication of International Hormesis SocietyArticle
- 5 Reasons Why Scoliosis X-Rays Are Not Harmful.Dose-response : a publication of International Hormesis SocietyArticle
- Repeat Radiography in Monitoring Structural Changes in the Treatment of Spinal Disorders in Chiropractic and Manual Medicine Practice: Evidence and Safety.Dose-response : a publication of International Hormesis SocietyArticle
- Application of Low Doses of Ionizing Radiation in Medical Therapies.Dose-response : a publication of International Hormesis SocietyArticle
- Are Restrictive Medical Radiation Imaging Campaigns Misguided? It Seems So: A Case Example of the American Chiropractic Association's Adoption of "Choosing Wisely".Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
X-ray therapy was used to treat pertussis/whooping cough during a 13-year period from 1923 to 1936 in North America and Europe. Twenty studies from clinicians in the United States reported that approximately 1500 cases of pertussis were treated by X-ray therapy usually with less than 0.5 erythema dose. Young children (<3 years) comprised about 70% to 80% of the cases, with the age of cases ranging from as young as 1 month to 50 years. In general, symptoms of severe coughing, vomiting episodes, and spasms were significantly relieved in about 85% of cases following up to 3 treatments, while about 15% of the cases showed nearly full relief after only 1 treatment. The X-ray therapy was also associated with a marked reduction in mortality of young (<3 years) children by over 90%. Despite such reported clinical success from a wide range of experienced researchers, the use of X-rays for the treatment of pertussis in young children was controversial, principally due to concerns of exposure to the thymus and thyroid even with the availability of lead shielding. By the mid-1930s, the treatment of pertussis cases via vaccine therapy came to dominate the therapeutic arena, and the brief era of a radiotherapy option for the treatment of pertussis ended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.