ArticleInternational journal of biological sciences2017
MiR-696 Regulates C2C12 Cell Proliferation and Differentiation by Targeting CNTFRα.
Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Inhibition of Sesn2 has negative regulatory effects on the myogenic differentiation of C2C12 myoblasts.Molecular biomedicine · 2024Article
- MicroRNA-142a-3p regulates neurogenic skeletal muscle atrophy by targeting Mef2a.Molecular therapy. Nucleic acids · 2023Article
- A Specific microRNA Targets an Elongase of Very Long Chain Fatty Acids to Regulate Fatty Acid Composition and Mitochondrial Morphology of Skeletal Muscle Cells.Animals : an open access journal from MDPI · 2022Article
- MiR-22-3p Inhibits Proliferation and Promotes Differentiation of Skeletal Muscle Cells by Targeting IGFBP3 in Hu Sheep.Animals : an open access journal from MDPI · 2022Article
- A polymorphism in porcine miR-22 is associated with pork color.Frontiers in veterinary science · 2022Article
- A Pillar-Based High-Throughput Myogenic Differentiation Assay to Assess Drug Safety.Molecules (Basel, Switzerland) · 2021Article
- MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway.Neural regeneration research · 2021Article
- MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.Skeletal muscle · 2021Article
- miR-196b-5p inhibits proliferation of Wharton's jelly umbilical cord stem cells.FEBS open bio · 2021Article
- A Chemically Defined Common Medium for Culture of C2C12 Skeletal Muscle and Human Induced Pluripotent Stem Cell Derived Spinal Spheroids.Cellular and molecular bioengineering · 2020Article
- GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRα.Development (Cambridge, England) · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Micro-696 (miR-696) has been previously known as an exercise related miRNA, which has a profound role in fatty acid oxidation and mitochondrial biogenesis of skeletal muscle. However, its role in skeletal myoblast proliferation and differentiation is still unclear. In this study, we found that miR-696 expressed highly in skeletal muscle and reduced during C2C12 myoblasts differentiation. MiR-696 overexpression repressed C2C12 myoblast proliferation and myofiber formation, while knockdown of endogenous miR-696 expression showed opposite results. During myogenesis, we observed an inversed expression pattern between miR-696 and CNTFRα in
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