Evidence map›Paper›PMID 28529413›Full record

ArticleJournal of cutaneous and aesthetic surgery

Autologous Platelet-rich Fibrin Matrix in Non-healing Trophic Ulcers in Patients with Hansen's Disease.

Umashankar Nagaraju, Priya K Sundar, Priyanka Agarwal, Belliappa P Raju, Mahesh Kumar

Open access · diamondAbstract read
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Article in Journal of cutaneous and aesthetic surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. L-PRF in extra-oral wound care.Periodontology 2000 · 2025
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  3. Iranian journal of microbiology · 2024
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  4. Article
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  6. Platelet-Rich Fibrin, Preparation and Use in Dermatology.Indian dermatology online journal · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Platelet-Rich Plasma: The Journey so Far !Indian dermatology online journal
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Umashankar NagarajuDepartment of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India.
Priya K SundarDepartment of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India.
Priyanka AgarwalDepartment of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India.
Belliappa P RajuDepartment of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India.
Mahesh KumarDepartment of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India.
Rajarajeswari Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers.

aimThe objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease.

designA prospective study.

settingAn institution-based clinic.

participantsSeven treated patients with Hansen's disease, with a mean age of 38.33 years, with nine non-healing trophic ulcer of more than 6 weeks duration. MEASUREMENTS: Photographs were taken before treatment and at every subsequent sitting. Area and volume were calculated at baseline and every subsequent sitting till the closure was achieved. MATERIALS AND

methodsThe healthy ulcers were treated with PRFM at weekly intervals, repeated once a week for a maximum of five sittings as per requirement.

resultsThe mean percentage improvement in the area was 93.52%, and volume was 97.74% at the end of the second sitting. All ulcers closed by a maximum of five sittings. No adverse events were noted.

conclusionPRFM for the treatment of trophic ulcers in treated patients with Hansen's disease is a feasible, safe, simple and inexpensive method.

Indexed as

Hansen's diseaseplatelet-rich fibrin matrixtrophic ulcer

Identifiers

PMID28529413
PMCPMC5418979
OpenAlexW2605730163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.