Evidence map›Paper›PMID 28529173›Full record

ReviewNeuroscience letters2018

What's in a context? Cautions, limitations, and potential paths forward.

Shauna M Stark, Zachariah M Reagh, Michael A Yassa, Craig E L Stark

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Sex differences in the context dependency of episodic memory.Frontiers in behavioral neuroscience · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neural measures associated with configural threat acquisition.Neurobiology of learning and memory · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shauna M StarkDepartment of Neurobiology & Behavior, University of California, Irvine, United States; Center for the Neurobiology of Learning and Memory, University of California, Irvine, United States.
Zachariah M ReaghDepartment of Neurobiology & Behavior, University of California, Irvine, United States; Center for the Neurobiology of Learning and Memory, University of California, Irvine, United States.
Michael A YassaDepartment of Neurobiology & Behavior, University of California, Irvine, United States; Center for the Neurobiology of Learning and Memory, University of California, Irvine, United States. Electronic address: myassa@uci.edu.
Craig E L StarkDepartment of Neurobiology & Behavior, University of California, Irvine, United States; Center for the Neurobiology of Learning and Memory, University of California, Irvine, United States. Electronic address: cestark@uci.edu.

Funding

UC Irvine Alzheimer's Disease Research Center Induced Pluripotent Stem Cell CoreP50AG016573 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI LAFERLA, FRANK M · 2000 to 2019
$37.0M
UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
Neuroimaging biomarkers for cognitive decline in elderly with amyloid pathologyR01AG053555 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Michael A Yassa · 2017 to 2026
$17.0M
Training in the Neurobiology of Aging and Alzheimers DiseaseT32AG000096 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI VIVEK SWARUP, Craig E Stark · 1985 to 2026
$9.6M
High-resolution Structural and Functional Brain Imaging of the Medial Temporal LoR01AG034613 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E · 2009 to 2018
$4.6M
Neural Mechanisms of Emotional Memory Modulation in Major DepressionR01MH102392 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI YASSA, MICHAEL A · 2014 to 2018
$1.9M
Neurophysiological And Fmri Studies Of Associative Learning In The Mtl And StriatR01MH085828 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E, SUZUKI, WENDY A. · 2010 to 2014
$1.9M
Selective age-related vulnerability in human perirhinal and lateral entorhinal corticesR21AG049220 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI YASSA, MICHAEL A · 2015 to 2016
$425k
EVALUATION OF CHD IN MEN AND WOMEN PRIOR TO FIRST AMIR01HS010239 · AHRQ · OLMSTED MEDICAL CENTER · PI YAWN, BARBARA P · 2000 to 2002
–
AHRQ HHS R01 HS010239NIA NIH HHS P30 AG010129NIA NIH HHS P50 AG016573NIA NIH HHS R01 AG034613NIA NIH HHS R01 AG053555NIA NIH HHS R21 AG049220NIA NIH HHS T32 AG000096NIMH NIH HHS R01 MH085828NIMH NIH HHS R01 MH102392
6 · The paper itself

Abstract

The purpose of memory is to guide current and future behavior based on previous experiences. Part of this process involves either discriminating between or generalizing across similar experiences that contain overlapping conditions (such as space, time, or internal state), which we often conceptualize as "contexts". In this review, we highlight major challenges facing the field as we attempt a neuroscience-based approach to the study of context and its impact on learning and memory. Here, we review some of the methodologies and approaches used to investigate context in both animals and humans, including the neurobiological mechanisms involved. Finally, we propose three tenets for operationalizing context in the experimental setting: 1) contexts must be stable over time along an experiential dimension; 2) contexts must be at least moderately complex in nature and their representations must be modifiable or adaptable, and 3) contexts must have some behavioral relevance (be it overt or incidental) so that its role can be measured.

Indexed as

AssociationMemory, EpisodicAnimalsHippocampusHumansAssociationsBindingContextHippocampusItems

Identifiers

PMID28529173
PMCPMC5735015

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.