ReviewTrends in genetics : TIG2017
Perspectives on Gene Regulatory Network Evolution.
Review in Trends in genetics : TIG, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed.
- Gene clustering drives the transcriptional coherence of disparate biological processes in eukaryotes.iScience · 2026Article
- Truncated Life History Underlies Rapid Local Adaptation in Island Rattlesnake Venom Expression.Genome biology and evolution · 2026Article
- Gene regulatory networks: from correlative models to causal explanations.Nature reviews. Genetics · 2026Review
- Beyond Mendel: a call to revisit the genotype-phenotype map through new experimental paradigms.Genetics · 2026Article
- Opposing insulin signals underlie the same developmental switch across hemipteran insects.Science advances · 2026Article
- Evolutionary Transitions in Social Behavior are Associated With Convergent and Partially Reversible Expansions of Transcription Factor Binding Sites.Genome biology and evolution · 2026Article
- Conserved Gene Expression Plasticity in Development Is More Pervasive Than Expression Divergence Between Species of Caenorhabditis Nematodes.Evolution & development · 2025Article
- Co-option of transcription factors drives evolution of quantitative disease resistance against a necrotrophic pathogen.The Plant cell · 2025Article
- Developmental rewiring of the NGAL/CUC/KLU network associated with pleiotropic roles of NGAL genes.The Plant journal : for cell and molecular biology · 2025Article
- GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model.Cell research · 2024Article
- Understanding developmental system drift.Development (Cambridge, England) · 2024Review
- The genetic regulatory architecture and epigenomic basis for age-related changes in rattlesnake venom.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Hybrid Epigenomes Reveal Extensive Local Genetic Changes to Chromatin Accessibility Contribute to Divergence in Embryonic Gene Expression Between Species.Molecular biology and evolution · 2023Article
- Modularity of biological systems: a link between structure and function.Journal of the Royal Society, Interface · 2023Article
- Modularity of biological systems: a link between structure and function.bioRxiv : the preprint server for biology · 2023Article
- Article
- A gene regulatory network inference model based on pseudo-siamese network.BMC bioinformatics · 2023Article
- The genetic basis of wing spots in Pieris canidia butterflies.BMC genomics · 2023Article
- Early effects of gene duplication on the robustness and phenotypic variability of gene regulatory networks.BMC bioinformatics · 2022Article
- A synthetic synthesis to explore animal evolution and development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Animal development proceeds through the activity of genes and their cis-regulatory modules (CRMs) working together in sets of gene regulatory networks (GRNs). The emergence of species-specific traits and novel structures results from evolutionary changes in GRNs. Recent work in a wide variety of animal models, and particularly in insects, has started to reveal the modes and mechanisms of GRN evolution. I discuss here various aspects of GRN evolution and argue that developmental system drift (DSD), in which conserved phenotype is nevertheless a result of changed genetic interactions, should regularly be viewed from the perspective of GRN evolution. Advances in methods to discover related CRMs in diverse insect species, a critical requirement for detailed GRN characterization, are also described.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.