Evidence map›Paper›PMID 28528688›Full record

ReviewMutation research. Reviews in mutation research

Human papillomavirus molecular biology.

Mallory E Harden, Karl Munger

Open access · greenAbstract readReview
In one paragraph

Review in Mutation research. Reviews in mutation research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 1 synthesis or guideline pooled it, 254 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Role of E5 from HPV16 in the Evasion of the Immune Response.International journal of molecular sciences · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  18. Review
  19. Article
  20. Review

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mallory E HardenProgram in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA, 02115, USA; Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, 02111, USA.
Karl MungerDepartment of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, MA, 02111, USA. Electronic address: karl.munger@tufts.edu.
Tufts University · US

Funding

BIOLOGICAL ACTIVITY OF HPV E7 IN HUMAN EPITHELIAL CELLSR01CA066980 · NCI · TUFTS UNIVERSITY BOSTON · PI MUNGER, KARL · 1996 to 2019
$7.4M
Perturbation of a cellular microRNA by human papillomavirus type 16.F31CA180516 · NCI · HARVARD MEDICAL SCHOOL · PI HARDEN, MALLORY ELLEN · 2013 to 2015
$99k
NCI NIH HHS F31 CA180516NCI NIH HHS R01 CA066980
6 · The paper itself

Abstract

Human papillomaviruses are small DNA viruses with a tropism for squamous epithelia. A unique aspect of human papillomavirus molecular biology involves dependence on the differentiation status of the host epithelial cell to complete the viral lifecycle. A small group of these viruses are the etiologic agents of several types of human cancers, including oral and anogenital tract carcinomas. This review focuses on the basic molecular biology of human papillomaviruses.

Indexed as

Carcinoma, Squamous CellEpitheliumGenome, ViralHumansMolecular BiologyMouth NeoplasmsNeoplasms, Squamous CellPapillomaviridaePapillomavirus VaccinesViral ProteinsPapillomavirus VaccinesViral ProteinsCervical cancerEpithelial differentiationHuman papillomavirusOncogeneTumor suppressorVaccine

Identifiers

PMID28528688
PMCPMC5500221
OpenAlexW2469801110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.