ArticleJournal of neuro-oncology2017
End of life care for glioblastoma patients at a large academic cancer center.
Article in Journal of neuro-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Defining end-of-life in glioblastoma multiforme: a systematic review.Journal of neuro-oncology · 2025Pooled it
- Palliative care in glioblastoma patients: a systematic review.Revista da Associacao Medica Brasileira (1992) · 2024Pooled it
- Palliative care and end-of-life care in adults with malignant brain tumors.Neuro-oncology · 2023Pooled it
- Duration of palliative care before death in international routine practice: a systematic review and meta-analysis.BMC medicine · 2020Pooled it
- Retrospective Characterization of Specialized Palliative Care in Patients With Gliomas.Journal of the advanced practitioner in oncology · 2026Article
- Association of performance status, depression, and demographics with advance directive documentation in patients with glioblastoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Early Palliative Care in Patients with Glioblastoma: Co-Design of an Integrated Care Pathway.Healthcare (Basel, Switzerland) · 2025Article
- Spirituality in Professional Patient-Centered Care for Adults with Primary Brain Tumors: An Exploratory Scoping Review.Journal of religion and health · 2025Article
- The impact of palliative care contact on the use of hospital resources at the end of life for brain tumor patients; a nationwide register-based cohort study.Journal of neuro-oncology · 2025Article
- Clinician perspectives on integrating neuro-oncology and palliative care for patients with high-grade glioma.Neuro-oncology practice · 2024Article
- "Not me!" a qualitative, vignette-based study of nurses' and physicians' reactions to spiritual distress on neuro-oncological units.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Acceptability and feasibility of cognitive assessments with adults with primary brain cancer and brain metastasis: A systematic review.Neuro-oncology practice · 2023Review
- Effect of palliative care decisions making on hospital service use at end-of-life in patients with malignant brain tumors: a retrospective study.BMC palliative care · 2023Article
- Causes of Death and End-of-Life Care in Patients With Intracranial High-Grade Gliomas: A Retrospective Observational Study.Neurology · 2022Observational
- Palliative Care Service Utilization and Advance Care Planning for Adult Glioblastoma Patients: A Systematic Review.Cancers · 2021Review
- Advance directives and end-of-life care: knowledge and preferences of patients with brain Tumours from Anhui, China.BMC cancer · 2021Article
- [Ethics of resuscitation and end of life decisions].Notfall & rettungsmedizin · 2021Review
- Hospice Utilization in Elderly Patients With Brain Metastases.Journal of the National Cancer Institute · 2020Article
- Advance Care Planning Needs in Patients With Glioblastoma Undergoing Radiotherapy.Journal of pain and symptom management · 2018Article
- Hospice care, cancer-directed therapy, and Medicare expenditures among older patients dying with malignant brain tumors.Neuro-oncology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Glioblastoma (GBM) is a universally fatal disease, complicated by significant cognitive and physical disabilities, inherent to the disease course. The purpose of this study was to retrospectively analyze end-of-life care for GBM patients at an academic center and compare utilization of these services to national quality of care guidelines, with the goal of identifying opportunities to improve end-of-life care. Single center retrospective cohort study of GBM patients at Johns Hopkins Hospital (JHH) between 2009 and 2014, using electronic medical records and hospice records. Comprehensive medical record review of 100 randomly selected patients with GBM, who were actively treated at JHH. Secondary analysis of all JHH GBM patients (n = 45) who received hospice care at Gilchrist Services, our largest provider, during this time period. Of 100 patients, 76 were referred to hospice. Despite the poor survival and changes in mental capacity associated with this disease, only 40% of individuals had documentation of code status and only 17% had any documentation of advance directives (ADs). None had documentation by a health care provider of a formal symptom, psychosocial, or spiritual assessment at greater than 50% of clinic visits. Only 17% used chemotherapy in their last month of life. 37% were hospitalized in the last month of life for an average of 9 days. Of the Gilchrist Services patients, the median length of stay in hospice was 21 days and 64% of these patients died in their residence with hospice services. Documentation of palliative care and end-of-life measures could improve quality of care for GBM patients, especially in the use of ADs, symptom, spiritual, and psychosocial assessments, with earlier use of hospice to prevent end-of-life hospitalizations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.