ReviewGlobal heart2017
Interethnic Differences in Serum Lipids and Implications for Cardiometabolic Disease Risk in African Ancestry Populations.
Review in Global heart, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima-Media Thickness: An Individual Participant Data Meta-Analysis.Journal of the American Heart Association · 2022Pooled it
- Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits.Nature communications · 2022Pooled it
- Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study.BMC medicine · 2021Pooled it
- Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights From the SPRINT Trial.Circulation. Genomic and precision medicine · 2022Trial
- Racial and ethnic differences in controlling risk factors for cardiovascular disease among adults with obesity, 1999-2023.International journal of obesity (2005) · 2026Article
- Improvements in blood and fitness tracker biomarkers in a longitudinal real-world cohort of digital health platform users.PLOS digital health · 2026Article
- The influence of ethnicity and sex on lipid profile and cardiovascular risk factors: a population-based study.Lipids in health and disease · 2026Article
- Comparative Analysis of White and African American Groups Reveals Unique Lipid and Inflammatory Features of Diabetes.Journal of racial and ethnic health disparities · 2025Article
- Differences in metabolic adaptations during mid and late pregnancy: a comparative cohort study between Rwanda and Germany.Journal of global health · 2025Article
- Cardiovascular Disease Burden among African Migrants.Current atherosclerosis reports · 2025Review
- Obesity phenotypes and dyslipidemia in adults from four African countries: An H3Africa AWI-Gen study.PloS one · 2025Article
- Article
- Nonlinear association of cardiometabolic index with hyperuricemia: insights from the NHANES 1999-2018 study.Frontiers in endocrinology · 2025Article
- Influence of Common Gene Variants on Lipid Levels and Risk of Coronary Heart Disease in Afro-Caribbeans.International journal of molecular sciences · 2024Article
- Lipidomics profiling and circulating triglyceride concentrations in sub-Saharan African individuals.Scientific reports · 2024Article
- The Triglyceride/HDL Ratio as a Surrogate Biomarker for Insulin Resistance.Biomedicines · 2024Review
- Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations.European journal of human genetics : EJHG · 2024Article
- International Migration and Cardiovascular Health: Unraveling the Disease Burden Among Migrants to North America and Europe.Journal of the American Heart Association · 2024Review
- Ethnic variations in metabolic syndrome components and their associations with the gut microbiota: the HELIUS study.Genome medicine · 2024Article
- Vitamin D/Bone Mineral Density and Triglyceride Paradoxes Seen in African Americans: A Cross-Sectional Study and Review of the Literature.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
African Americans generally have a healthier lipid profile (lower triglycerides and higher high-density lipoprotein cholesterol concentration) compared with those of other ethnicities. Paradoxically, African Americans do not experience a decreased risk of the cardiometabolic diseases that serum lipids are expected to predict. This review explores this mismatch between biomarker and disease among African ancestry individuals by investigating the presence of interethnic differences in the biological relationships underlying the serum lipids-disease association. This review also discusses the physiologic and genomic factors underlying these interethnic differences. Additionally, because of the importance of serum lipids in assessing disease risk, interethnic differences in serum lipids have implications for identifying African ancestry individuals at risk of cardiometabolic disease. Where possible, data from Africa is included, to further elucidate these ancestral differences in the context of a different environmental background.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.