Evidence map›Paper›PMID 28527878›Full record

ReviewChest2017

Obstructive Sleep Apnea and Diabetes: A State of the Art Review.

Sirimon Reutrakul, Babak Mokhlesi

2 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chest, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 376 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
376citing papers in PubMed, 12 pooled it
21.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04917094 nacompletednot on this mapstarted 2021, after this paper: background citation

Effectiveness of Compression Stocking on Overnight Fluid Shift in Obstructive Sleep Apnea Patients

TypeinterventionalSponsorKhoo Teck Puat HospitalRan2021 to 2022Enrolled29ConditionsObstructive Sleep ApneaArmsCompression stocking
NCT06766760 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Pilot Study of Single-port Robot-assisted Surgery Using da Vinci SP Surgical System for the Surgical Treatment for Patients With Obstructive Sleep Apnea

TypeinterventionalSponsorChang Gung Memorial HospitalRan2025 to 2026Enrolled25ConditionsObstructive Sleep ApneaArmsDa Vinci SP Surgical System, Model SP1098
3 · Its place in the literature

Who cites it

376 citing papers in PubMed, 12 syntheses or guidelines pooled it, 644 citations in OpenAlex.

  1. Pooled it
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  10. Guideline
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  13. Trial
  14. Article
  15. Article
  16. Observational
  17. Beyond coexistence: attempting to unlock the diabetes-COMISA Link.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  18. Article
  19. Diabetes mellitus is associated with increased prevalence and severity of COMISA: evidence from the nationwide TURKAPNE cohort.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Observational
  20. Article

316 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Sirimon ReutrakulDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois College of Medicine at Chicago, Chicago, IL.
Babak MokhlesiSection of Pulmonary and Critical Care, Sleep Disorders Center, Department of Medicine, The University of Chicago, Chicago, IL. Electronic address: bmokhles@medicine.bsd.uchicago.edu.
Illinois College · USUniversity of Chicago · US

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
Impact of Sleep in the Restoring Insulin Secretion (RISE) StudyR01HL119161 · NHLBI · UNIVERSITY OF CHICAGO · PI MOKHLESI, BABAK · 2013 to 2016
$1.5M
NHLBI NIH HHS R01 HL119161NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

OSA is a chronic treatable sleep disorder and a frequent comorbidity in patients with type 2 diabetes. Cardinal features of OSA, including intermittent hypoxemia and sleep fragmentation, have been linked to abnormal glucose metabolism in laboratory-based experiments. OSA has also been linked to the development of incident type 2 diabetes. The relationship between OSA and type 2 diabetes may be bidirectional in nature given that diabetic neuropathy can affect central control of respiration and upper airway neural reflexes, promoting sleep-disordered breathing. Despite the strong association between OSA and type 2 diabetes, the effect of treatment with CPAP on markers of glucose metabolism has been conflicting. Variability with CPAP adherence may be one of the key factors behind these conflicting results. Finally, accumulating data suggest an association between OSA and type 1 diabetes as well as gestational diabetes. This review explores the role of OSA in the pathogenesis of type 2 diabetes, glucose metabolism dysregulation, and the impact of OSA treatment on glucose metabolism. The association between OSA and diabetic complications as well as gestational diabetes is also reviewed.

Indexed as

ComorbidityDiabetes Mellitus, Type 2Global HealthHumansPrevalencePreventive MedicineRisk FactorsSleep Apnea, Obstructivecentral sleep apneadiabetic complicationsgestational diabetesOSAsleep apneatype 1 diabetestype 2 diabetesweight loss

Identifiers

PMID28527878
PMCPMC5812754
OpenAlexW2735970289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.