Evidence map›Paper›PMID 28527736›Full record

ArticleJournal of controlled release : official journal of the Controlled Release Society2017

The effects of non-invasive radiofrequency electric field hyperthermia on biotransport and biodistribution of fluorescent [60]fullerene derivative in a murine orthotopic model of breast adenocarcinoma.

Norman A Lapin, Martyna Krzykawska-Serda, Sean Dilliard, Yuri Mackeyev, Maciej Serda, Lon J Wilson, Steven A Curley, Stuart J Corr

Abstract read
In one paragraph

Article in Journal of controlled release : official journal of the Controlled Release Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. ACS biomaterials science & engineering · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Development of photoactive Sweet-CNanomedicine (London, England) · 2018
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Norman A LapinMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Martyna Krzykawska-SerdaMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA; Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków 30-387, Poland.
Sean DilliardMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005, USA.
Yuri MackeyevDepartment of Chemistry, Rice University, Houston, TX 77005, USA.
Maciej SerdaDepartment of Chemistry, Rice University, Houston, TX 77005, USA; Institute of Chemistry, University of Silesia in Katowice, 40-006 Katowice, Poland.
Lon J WilsonDepartment of Chemistry, Rice University, Houston, TX 77005, USA.
Steven A CurleyMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA; Department of Mechanical Engineering and Materials Science, Rice University, Houston, TX 77005, USA.
Stuart J CorrMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA; Department of Chemistry, Rice University, Houston, TX 77005, USA; Department of Biomedical Engineering, University of Houston, Houston, TX 77204, USA. Electronic address: stuart.corr@bcm.edu.

Funding

TRANS-NETWORK PROJECTSU54CA143837 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FERRARI, MAURO · 2009 to 2014
$10.8M
NCI NIH HHS U54 CA143837
6 · The paper itself

Abstract

The aim of this study is to understand the combined and differential biokinetic effects of radiofrequency (RF) electric-field hyperthermia as an adjunctive therapy to [60]fullerene nanoparticle-based drug delivery systems in targeting the micro-vasculature and micro-environments of breast cancer tumors. Intravital microscopy (IVM) is an ideal tool to provide the spatial and temporal resolution needed for quantification in this investigation. The water-soluble and fluorescent [60]fullerene derivative (C

Indexed as

Hyperthermia, InducedAdenocarcinomaAnimalsBiological TransportCell Line, TumorCombined Modality TherapyDrug Delivery SystemsFemaleFullerenesMammary Neoplasms, ExperimentalMice, Inbred BALB CMice, NudeTissue DistributionFullerenes[60]FullereneChemotherapyDrug pharmacokineticsHyperthermiaIntravital microscopyRadiofrequency

Identifiers

PMID28527736
PMCPMC5549922

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.