Evidence map›Paper›PMID 28527140›Full record

ArticleEnvironmental science and pollution research international2017

Effect of tannery effluent on oxidative status of brain structures and liver of rodents.

Felipe Dos Santos Moysés, Karine Bertoldi, Viviane Rostirola Elsner, Laura Reck Cechinel, Carla Basso, Simone Stülp, Marco Antônio Siqueira Rodrigues, Ionara Rodrigues Siqueira

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felipe Dos Santos MoysésPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Karine BertoldiPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Viviane Rostirola ElsnerPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Laura Reck CechinelPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Carla BassoPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Simone StülpPrograma de Pós-Graduação em Ambiente e Desenvolvimento, Univates, Lajeado, RS, Brazil.
Marco Antônio Siqueira RodriguesPrograma de Pós-Graduação em Qualidade Ambiental, Universidade Feevale - FEEVALE, Novo Hamburgo, RS, Brazil.
Ionara Rodrigues SiqueiraPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. ionara@ufrgs.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress has been considered as a central mechanism of toxicity induced by xenobiotics. Previously, it was demonstrated that mice exposed to tannery effluent showed an anxiety-like behavior, without any comparable behavioral effects in rats. The aim of the present study was to investigate the impact of tannery wastewater on oxidative status in in vitro and in vivo assays with two mammal species, mice and rats. Specifically, homogenates of two brain areas and the liver were incubated with tannery wastewater; reactive species and lipid peroxidation levels and antioxidant enzyme activities were detected. In addition, the effects of in vivo exposure of mice to tannery effluents on and lipid peroxidation levels and the total reactive antioxidant capacity in brain areas and liver. Brain areas, the hippocampus and frontal cortex, and the liver of mice exposed to tannery wastewater showed oxidative stress. Our data suggest that divergent species-dependent hepatic enzymes adaptations, such as glutathione peroxidase and glutathione S-transferase activities, induced by tannery effluent could explain previous behavioral findings.

Indexed as

AntioxidantsIndustrial WasteOxidative StressAnimalsBrainCatalaseGlutathioneGlutathione PeroxidaseLipid PeroxidationLiverMiceOxidation-ReductionRatsSuperoxide DismutaseWastewaterWater Pollutants, ChemicalAntioxidantsCatalaseGlutathioneGlutathione PeroxidaseIndustrial WasteSuperoxide DismutaseWastewaterWater Pollutants, ChemicalGlutathione peroxidaseGlutathione S-transferaseMiceOxidative stressRatTannery effluent

Identifiers

PMID28527140

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.