ArticleMarine biotechnology (New York, N.Y.)2017
A Genome-Wide Association Study Identifies the Genomic Region Associated with Shell Color in Yesso Scallop, Patinopecten yessoensis.
Article in Marine biotechnology (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 84 citations in OpenAlex.
- Genetic Parameter Estimates for Growth, Meat Yield and Foot Color Traits of Pacific AbaloneAnimals : an open access journal from MDPI · 2026Article
- Identification of Key Biomarkers of Growth-Related Traits in the Bay Scallop Argopecten irradians irradians via Multi-omics Analysis Strategies.Marine biotechnology (New York, N.Y.) · 2025Article
- Tracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach.Communications biology · 2024Article
- Genomic diversity of wild and cultured Yesso scallop Mizuhopecten yessoensis from Japan and Canada.G3 (Bethesda, Md.) · 2023Article
- Fine mapping of the Cepaea nemoralis shell colour and mid-banded loci using a high-density linkage map.Heredity · 2023Article
- Genome-Wide Association Study on the Content of Nucleotide-Related Compounds in Korean Native Chicken Breast Meat.Animals : an open access journal from MDPI · 2023Article
- Association of single-nucleotide polymorphisms in dual specificity phosphatase 8 and insulin-like growth factor 2 genes with inosine-5'-monophosphate, inosine, and hypoxanthine contents in chickens.Animal bioscience · 2023Article
- The first high-density genetic map of common cockle (Cerastoderma edule) reveals a major QTL controlling shell color variation.Scientific reports · 2022Article
- Article
- Identification of shell-color-related microRNAs in the Manila clam Ruditapes philippinarum using high-throughput sequencing of small RNA transcriptomes.Scientific reports · 2021Article
- Genome-Wide Association Study RevealsFrontiers in genetics · 2021Article
- Histological and Expression Differences Among Different Mantle Regions of the Yesso Scallop (Patinopecten yessoensis) Provide Insights into the Molecular Mechanisms of Biomineralization and Pigmentation.Marine biotechnology (New York, N.Y.) · 2019Article
- Mapping and Validating QTL for Fatty Acid Compositions and Growth Traits in Asian Seabass.Marine biotechnology (New York, N.Y.) · 2019Article
- Analysis of genome-wide SNPs based on 2b-RAD sequencing of pooled samples reveals signature of selection in different populations ofJournal of biosciences · 2019Article
- Genome-wide association analysis of nutrient traits in the oyster Crassostrea gigas: genetic effect and interaction network.BMC genomics · 2019Article
- QTL Mapping for Red Blotches in Malaysia Red Tilapia (Oreochromis spp.).Marine biotechnology (New York, N.Y.) · 2019Article
- Transcriptomic and proteomic analyses of genetic factors influencing adductor muscle coloration in QN Orange scallops.BMC genomics · 2019Article
- Identifying a Long QTL Cluster Across chrLG18 Associated with Salt Tolerance in Tilapia Using GWAS and QTL-seq.Marine biotechnology (New York, N.Y.) · 2019Article
- Association and Functional Analyses Revealed That PPP1R3B Plays an Important Role in the Regulation of Glycogen Content in the Pacific OysterFrontiers in genetics · 2019Article
- The FTO Gene Is Associated with Growth and Omega-3/-6 Ratio in Asian Seabass.Marine biotechnology (New York, N.Y.) · 2018Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The shell color polymorphism widely exists in economic shellfish, which not only results in a better visual perception but also shows great value as an economic trait for breeding. Small numbers of reddish-orange shell Yesso scallops, Patinopecten yessoensis, were found in cultured populations compared to the brown majority. In this study, a genome-wide association study was conducted to understand the genetic basis of shell color. Sixty-six 2b-RAD libraries with equal numbers of reddish-orange and brown shell individuals were constructed and sequenced using the Illumina HiSeq 2000 platform. A total of 322,332,684 high-quality reads were obtained, and the average sequencing depth was 18.4×. One genomic region on chromosome 11 that included 239 single-nucleotide polymorphisms (SNPs) was identified as significantly associated with shell color. After verification by high-resolution melting in another population, two SNPs were selected as specific loci for reddish-orange shell color. These two SNPs could be used to improve the selective breeding progress of true-breeding strains with complete reddish-orange scallops. In addition, within the significantly associated genomic region, candidate genes were identified using marker sequences to search the draft genome of Yesso scallop. Three genes (LDLR, FRIS, and FRIY) with known functions in carotenoid metabolism were identified. Further study using high-performance liquid chromatography proved that the relative level of carotenoids in the reddish-orange shells was 40 times higher than that in the brown shells. These results suggested that the accumulation of carotenoids contributes to the formation of reddish-orange shells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.