ArticleJournal of the American Society of Nephrology : JASN2017
The Phenotypic Spectrum of Nephropathies Associated with Mutations in Diacylglycerol Kinase
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Tenth Special Issue.Journal of clinical apheresis · 2026Guideline
- Pneumococcal HUS in infancy masking DGKE-related thrombotic microangiopathy with secondary hemophagocytic lymphohistiocytosis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Thrombotic microangiopathy after kidney transplantation: diagnosis and management strategies.Clinical kidney journal · 2026Review
- Article
- Complement diagnostics and therapeutics for the pediatric population: early successes and opportunities for further advancement.Frontiers in pharmacology · 2026Review
- Glycerophospholipids: Roles in Cell Trafficking and Associated Inborn Errors.Journal of inherited metabolic disease · 2025Review
- Outcomes from the International Society of Nephrology Hemolytic Uremic Syndromes International Forum.Kidney international · 2024Article
- The Role of Genetic Testing in Adult CKD.Journal of the American Society of Nephrology : JASN · 2024Article
- Observational
- Clinical features and outcomes of patients with diacylglycerol kinase epsilon nephropathy: a nationwide experience.Pediatric nephrology (Berlin, Germany) · 2023Article
- Clinical features and management of atypical hemolytic uremic syndrome patient withFrontiers in pediatrics · 2023Review
- Diacylglycerol kinase epsilon protects against renal ischemia/reperfusion injury in mice through Krüppel-like factor 15/klotho pathway.Renal failure · 2022Article
- Novel Complement Factor B Gene Mutation Identified in a Kidney Transplant Recipient with a Shiga Toxin-Triggered Episode of Thrombotic Microangiopathy.The American journal of case reports · 2022Article
- Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022Article
- A rare cause of membranoproliferative patterns of injury in siblings with steroid-resistant nephrotic syndrome: Answers.Pediatric nephrology (Berlin, Germany) · 2021Article
- Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics.Nature reviews. Nephrology · 2021Review
- The Syndromes of Thrombotic Microangiopathy: A Critical Appraisal on Complement Dysregulation.Journal of clinical medicine · 2021Review
- A patient with a homozygous diacylglycerol kinase epsilon (DGKE) gene mutation with atypical haemolytic uraemic syndrome and low C3 responded well to eculizumab: a case report.BMC nephrology · 2021Article
- Nephrotic syndrome in a 7-year-old girl with atypical hemolytic uremic syndrome relapse: Answers.Pediatric nephrology (Berlin, Germany) · 2021Article
- Making the Correct Diagnosis in Thrombotic Microangiopathy: A Narrative Review.Canadian journal of kidney health and disease · 2021Review
Corrections and comments
- Erratum issuedErratum.2017
Authors and funding
23 authors at 14 institutions in 9 countries.
Karolis AzukaitisClinic of Pediatrics, Faculty of Medicine, Vilnius University, Vilnius, Lithuania; k.azukaitis@gmail.com.
Eva SimkovaPediatric Nephrology Department, Dubai Hospital, Dubai, United Arab Emirates.
Mohammad Abdul MajidPediatric Nephrology Department, Dubai Hospital, Dubai, United Arab Emirates.
Matthias GalianoDepartments of Pediatrics and Adolescent Medicine, and.
Kerstin BenzDepartments of Pediatrics and Adolescent Medicine, and.
Kerstin AmannNephropathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Clemens BockmeyerNephropathology, Institute of Pathology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Radha GajjarDivision of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Kevin E MeyersDivision of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Hae Il CheongDepartment of Paediatrics, Seoul National University Children's Hospital, Seoul, Korea.
Bärbel Lange-SperandioDivision of Pediatric Nephrology, Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians University, Munich, Germany.
Therese JungraithmayrPediatric Nephrology Center, Klinikum Memmingen, Memmingen, Germany.
Véronique Frémeaux-BacchiDepartment of Immunology, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, Paris, France.
Carsten BergmannCenter for Human Genetics, Bioscientia, Ingelheim, Germany.
Csaba BereczkiDepartment of Pediatrics, University of Szeged, Szeged, Hungary.
Monika MiklaszewskaDepartment of Pediatric Nephrology, Jagiellonian University Medical College, Cracow, Poland.
Dorottya CsukaThird Department of Internal Medicine, Research Laboratory and George Füst Complement Diagnostic Laboratory, Semmelweis University, Budapest, Hungary.
Zoltán ProhászkaThird Department of Internal Medicine, Research Laboratory and George Füst Complement Diagnostic Laboratory, Semmelweis University, Budapest, Hungary.
Paul Killen
Patrick GipsonNephrology Division, Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan.
Matthew G SampsonNephrology Division, Department of Pediatrics, University of Michigan School of Medicine, Ann Arbor, Michigan.
Mathieu LemaireProgram in Cell Biology, The Hospital for Sick Children Research Institute, Toronto, Canada.
Franz SchaeferDivision of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, Heidelberg University, Heidelberg, Germany.
Children's Hospital of Philadelphia · USDubai Hospital · AEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEOffice of Adolescent Health · USSemmelweis University · HUUniversity of Michigan · USGerman Center for Pediatric and Adolescent Rheumatology · DEHôpital Européen Georges-Pompidou · FRJagiellonian University · PLLudwig-Maximilians-Universität München · DESeoul National University Hospital · KRUniversity of Szeged · HUUniversity of Toronto · CAVilnius University · LT
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent discovery of mutations in the gene encoding diacylglycerol kinase
Indexed as
Atypical Hemolytic Uremic SyndromeChild, PreschoolDiacylglycerol KinaseDNA Mutational AnalysisFemaleGlomerulonephritis, MembranoproliferativeHumansIncidenceInfantLithuaniaMalePhenotypeDGKE protein, humanDiacylglycerol Kinaseatypical hemolytic uremic syndromeDGKEdiacylglycerol kinase epsilonmembranoproliferative glomerulonephritisthrombotic microangiopathy
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.