ArticleJournal of the American Heart Association2017
T-Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Utilization and Prognosis of Cardiac Device Implantation in AL Versus ATTR Amyloidosis.Pacing and clinical electrophysiology : PACE · 2026Article
- Spatial and temporal dispersion of ventricular repolarization in pediatric patients with congenital long QT syndrome.HeartRhythm case reports · 2026Article
- mROS‑calcium feedback loop promotes lethal ventricular arrhythmias and sudden cardiac death in early myocardial ischemia.International journal of molecular medicine · 2024Article
- The role of β-adrenergic stimulation in QT interval adaptation to heart rate during stress test.PloS one · 2023Article
- Article
- ECG T-Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low- and Moderate-Risk Populations.Journal of the American Heart Association · 2022Article
- Periodic repolarization dynamics as predictor of risk for sudden cardiac death in chronic heart failure patients.Scientific reports · 2021Article
- Arrhythmic Sudden Cardiac Death and the Role of Implantable Cardioverter-Defibrillator in Patients with Cardiac Amyloidosis-A Narrative Literature Review.Journal of clinical medicine · 2021Review
- Body Surface Mapping of Ventricular Repolarization Heterogeneity: AnFrontiers in physiology · 2020Article
- Noninvasive Mapping of the Electrophysiological Substrate in Cardiac Amyloidosis and Its Relationship to Structural Abnormalities.Journal of the American Heart Association · 2019Article
- Prediction of sudden death in elderly patients with heart failure.Journal of geriatric cardiology : JGC · 2018Review
- Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort.PloS one · 2017Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with chronic heart failure are at high risk of sudden cardiac death (SCD). Increased dispersion of repolarization restitution has been associated with SCD, and we hypothesize that this should be reflected in the morphology of the T-wave and its variations with heart rate. The aim of this study is to propose an electrocardiogram (ECG)-based index characterizing T-wave morphology restitution (TMR), and to assess its association with SCD risk in a population of chronic heart failure patients. METHODS AND
resultsHolter ECGs from 651 ambulatory patients with chronic heart failure from the MUSIC (MUerte Súbita en Insuficiencia Cardiaca) study were available for the analysis. TMR was quantified by measuring the morphological variation of the T-wave per RR increment using time-warping metrics, and its predictive power was compared to that of clinical variables such as the left ventricular ejection fraction and other ECG-derived indices, such as T-wave alternans and heart rate variability. TMR was significantly higher in SCD victims than in the rest of patients (median 0.046 versus 0.039,
conclusionsThis study shows that TMR is specifically associated with SCD in a population of chronic heart failure patients, and it is a better predictor than clinical and ECG-derived variables.
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