Evidence map›Paper›PMID 28526681›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Adoptive Transfer of Phosphoantigen-Specific γδ T Cell Subset Attenuates

Arwa Qaqish, Dan Huang, Crystal Y Chen, Zhuoran Zhang, Richard Wang, Shengpu Li, Enzhuoa Yang, Yang Lu, Michelle H Larsen, William R Jacobs and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 97 citations in OpenAlex.

  1. Trial
  2. Mucosal-associated invariant T cells and Vδ2Clinical and experimental immunology · 2020
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Arwa QaqishDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.ORCID 0000-0002-1228-961X
Dan HuangDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Crystal Y ChenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Zhuoran ZhangDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.ORCID 0000-0003-2266-8346
Richard WangDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Shengpu LiDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Enzhuoa YangDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Yang LuDepartment of Radiology, University of Illinois College of Medicine Chicago, Chicago, IL 60612; and.
Michelle H LarsenDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Lixia QianDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
James FrencherDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612.
Ling ShenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612; zchen@uic.edu lshen@uic.edu.
Zheng W ChenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine Chicago, Chicago, IL 60612; zchen@uic.edu lshen@uic.edu.
University of Illinois Urbana-Champaign · USAlbert Einstein College of Medicine · USIllinois College · US

Funding

MODEL OF AIDS VIRUS-RELATED PULMONARY TUBERCULOSISR01HL064560 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1999 to 2014
$9.5M
Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
Ag-specific gamma delta T cells and immunity to TB/AIDS-related TBR01OD015092 · OD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2013 to 2017
$3.0M
Anti-TB sterilizing immunity in immune and HIV+ individualsR01HL129887 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2015 to 2018
$2.1M
NHLBI NIH HHS R01 HL064560NHLBI NIH HHS R01 HL129887NIH HHS R01 OD015092
6 · The paper itself

Abstract

The dominant Vγ2Vδ2 T cell subset recognizes phosphoantigen and exists only in humans and nonhuman primates. Despite the discovery of γδ T cells >30 y ago, a proof-of-concept study has not been done to prove the principle that the Vγ2Vδ2 T cell subset is protective against

Indexed as

Adoptive TransferAnimalsBacterial LoadCytokinesImmunologic MemoryLungLymphocyte Function-Associated Antigen-1Macaca fascicularisMycobacterium tuberculosisPhosphoproteinsReceptors, Antigen, T-Cell, gamma-deltaReceptors, CCR5Receptors, CXCR3T-Lymphocyte SubsetsTuberculosisCytokinesLymphocyte Function-Associated Antigen-1PhosphoproteinsReceptors, Antigen, T-Cell, gamma-deltaReceptors, CCR5Receptors, CXCR3

Identifiers

PMID28526681
PMCPMC5557270
OpenAlexW2616106896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.