ArticleBMC endocrine disorders2017
Pulse wave velocity and cardiac autonomic function in type 2 diabetes mellitus.
Article in BMC endocrine disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of arterial stiffness and neuropathy in diabetes: a systematic review and meta-analysis.BMJ open diabetes research & care · 2023Pooled it
- Impact of supra-maximal interval training vs. high-intensity interval training on cardiac auto-regulation response in physically active adults.European journal of applied physiology · 2024Trial
- Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.Diabetes care · 2019 · on this mapTrial
- Association Between Carotid Arterial Strain and Heart Rate Variability in Older Age.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Epicardial adipose tissue volume and arterial stiffness in people living with diabetes: the METAB-CV-PWV study.Cardiovascular diabetology · 2025Article
- Artificial light at night affects the daily profile of pulse pressure and protein expression in the thoracic aorta of rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Baroreflex Sensitivity as a Surrogate Biomarker for Concurrently Assessing the Severity of Arterial Stiffness and Cardiovascular Autonomic Neuropathy in Individuals with Type 2 Diabetes.Journal of personalized medicine · 2024Article
- Autonomic dysfunction is associated with the development of arterial stiffness: the Whitehall II cohort.GeroScience · 2023Article
- Relationship between reduced heart rate variability and increased arterial stiffness evaluated by the cardio-ankle vascular index in people with type 2 diabetes.Diabetology international · 2023Article
- Diabetes Affects the Relationship between Heart Rate Variability and Arterial Stiffness in a Gender-Specific Manner.Journal of clinical medicine · 2022Article
- Vascular Age, Metabolic Panel, Cardiovascular Risk and Inflammaging in Patients With Rheumatoid Arthritis Compared With Patients With Osteoarthritis.Frontiers in cardiovascular medicine · 2022Article
- Variability of peripheral pulse wave velocity in patients with diabetes mellitus type 2 during orthostatic challenge.Physiological research · 2020Article
- Cardiovascular risk and heart rate variability in young adults with type 2 diabetes and arterial stiffness: The SEARCH for Diabetes in Youth Study.Journal of diabetes and its complications · 2020Article
- Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model.Diabetology & metabolic syndrome · 2020Article
- Pulse pressure amplification and cardiac autonomic dysfunction in patients with type 2 diabetes mellitus.Journal of human hypertension · 2018Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased carotid-femoral pulse wave velocity (PWV) has been associated with incident cardiovascular disease, independently of traditional risk factors. Cardiac autonomic dysfunction is a common complication of diabetes and has been associated with reduced aortic distensibility. However, the association of cardiac autonomic dysfunction with PWV is not known. In this study we examined the association between cardiac autonomic function and PWV in subjects with type 2 diabetes mellitus.
methodsA total of 290 patients with type 2 diabetes were examined. PWV was measured at the carotid-femoral segment with applanation tonometry. Central mean arterial blood pressure (MBP) was determined by the same apparatus. Participants were classified as having normal (n = 193) or abnormal (n = 97) PWV values using age-corrected values. Cardiac autonomic nervous system activity was determined by measurement of parameters of heart rate variability (HRV).
resultsSubjects with abnormal PWV were older, had higher arterial blood pressure and higher heart rate than those with normal PWV. Most of the values of HRV were significantly lower in subjects with abnormal than in those with normal PWV. Multivariate analysis, after controlling for various confounding factors, demonstrated that abnormal PWV was associated independently only with peripheral MBP [odds ratio (OR) 1.049, 95% confidence intervals (CI) 1.015-1.085, P = 0.005], central MBP (OR 1.052, 95% CI 1.016-1.088, P = 0.004), log total power (OR 0.490, 95% CI 0.258-0.932, P = 0.030) and log high frequency power (OR 0.546, 95% CI 0.301-0.991, P = 0.047).
conclusionsIn subjects with type 2 diabetes, arterial blood pressure and impaired cardiac autonomic function is associated independently with abnormal PWV.
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