Evidence map›Paper›PMID 28525533›Full record

ArticleAmerican journal of epidemiology2017

Phenol Concentrations During Childhood and Subsequent Measures of Adiposity Among Young Girls.

Andrea L Deierlein, Mary S Wolff, Ashley Pajak, Susan M Pinney, Gayle C Windham, Maida P Galvez, Michael Rybak, Antonia M Calafat, Lawrence H Kushi, Frank M Biro and 1 more

Abstract read
In one paragraph

Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Obesity and endocrine-disrupting chemicals.Endocrine connections · 2021
    Review
  14. Review
  15. Association of urinary chlorophenols with central obesity in Korean girls.Environmental science and pollution research international · 2021
    Article
  16. Association between urinary paraben concentrations and gestational weight gain during pregnancy.Journal of exposure science & environmental epidemiology · 2020
    Article
  17. Endocrine-disrupting chemicals: implications for human health.The lancet. Diabetes & endocrinology · 2020
    Review
  18. Review
  19. Postnatal exposure to household disinfectants, infant gut microbiota and subsequent risk of overweight in children.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrea L Deierlein
Mary S Wolff
Ashley Pajak
Susan M Pinney
Gayle C Windham
Maida P Galvez
Michael Rybak
Antonia M Calafat
Lawrence H Kushi
Frank M Biro
Susan L Teitelbaum

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI YADAV, JAGJIT S · 1992 to 2022
$35.4M
MSHS Translational Science HubUL1TR001433 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2015 to 2019
$26.6M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2014 to 2026
$21.3M
MOUNT SINAI INSTITUTES FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR029887 · NCRR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2009 to 2011
$19.2M
Bay Area Breast Cancer &the Environment Research CenterU01ES012801 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2003 to 2010
$12.4M
Center for Environment and Mammary Gland DevelopmentU01ES012771 · NIEHS · FOX CHASE CANCER CENTER · PI RUSSO, JOSE · 2003 to 2009
$11.1M
Puberty &Cancer Initiation: Environment Diet &ObesityU01ES012770 · NIEHS · UNIVERSITY OF CINCINNATI · PI BORNSCHEIN, ROBERT L · 2003 to 2009
$9.0M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
PRENATAL PCB EXPOSURE &NEURODEVELOPMENTAL OUTCOMES IN ADOLESCENCE &ADULTHOODP01ES009584 · NIEHS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI WOLFF, MARY S · 1999 to 2009
$7.3M
Environmental and Genetic Determinants of PubertyU01ES019454 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WOLFF, MARY S · 2010 to 2016
$5.8M
Breast Cancer and the Environment Research CenterU01ES012800 · NIEHS · MICHIGAN STATE UNIVERSITY · PI HASLAM, SANDRA Z · 2003 to 2009
$5.6M
Environmental Epigenetics on PubertyU01ES019453 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI BIRO, FRANK M · 2010 to 2015
$5.4M
Intramural CDC HHS CC999999NCATS NIH HHS UL1 TR001433NCRR NIH HHS UL1 RR029887NICHD NIH HHS T32 HD049311NIEHS NIH HHS P01 ES009584NIEHS NIH HHS P30 ES006096NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R00 ES023474NIEHS NIH HHS U01 ES012770NIEHS NIH HHS U01 ES012771NIEHS NIH HHS U01 ES012800NIEHS NIH HHS U01 ES012801NIEHS NIH HHS U01 ES019435NIEHS NIH HHS U01 ES019453NIEHS NIH HHS U01 ES019454NIEHS NIH HHS U01 ES019457
6 · The paper itself

Abstract

Phenolic compounds represent a class of environmental chemicals with potentially endocrine-disrupting capabilities. We investigated longitudinal associations between childhood exposure to phenols, from both manmade and natural sources, and subsequent measures of adiposity among girls enrolled in the Breast Cancer and the Environment Research Program between 2004 and 2007. Baseline (ages 6-8 years) urinary concentrations were obtained for creatinine and phenol metabolites: enterolactone, genistein, daidzein, benzophenone-3, bisphenol A, the sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichlorophenol, and triclosan. Body mass index (weight (kg)/height (m)2), waist circumference, and percent body fat were measured at annual or semiannual examinations through 2015 (n = 1,017). Linear mixed-effects regression was used to estimate how baseline concentrations of phenols (tertile groups) were related to changes in girls' adiposity measurements from ages 7 through 15 years. Enterolactone was inversely associated with body mass index, waist circumference, and percent body fat, while 2,5-dichlorophenol was positively associated with these measurements. A nonmonotonic association was observed for triclosan and girls' adiposity; however, it was due to effect modification by baseline overweight status. Triclosan was positively associated with adiposity only among overweight girls. These results suggest that exposure to specific phenols during childhood may influence adiposity through adolescence.

Indexed as

AdiposityAdolescentBody Mass IndexChildCreatinineEnvironmental ExposureFemaleHumansLinear ModelsLongitudinal StudiesNew YorkObesityOhioPhenolsSan FranciscoSocial ClassCreatininePhenolsadipositychildlongitudinal studiesphenol

Identifiers

PMID28525533
PMCPMC5600702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.