Evidence map›Paper›PMID 28525314›Full record

ArticleeLife2017

Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts.

Jorge M Santos, Saskia Egarter, Vanessa Zuzarte-Luís, Hirdesh Kumar, Catherine A Moreau, Jessica Kehrer, Andreia Pinto, Mário da Costa, Blandine Franke-Fayard, Chris J Janse and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Jorge M SantosInstituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, Lisbon, Portugal.ORCID 0000-0002-4940-5207
Saskia EgarterParasitology, Department of Infectious Diseases, University of Heidelberg Medical School, Heidelberg, Germany.
Vanessa Zuzarte-LuísInstituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, Lisbon, Portugal.
Hirdesh KumarParasitology, Department of Infectious Diseases, University of Heidelberg Medical School, Heidelberg, Germany.
Catherine A MoreauParasitology, Department of Infectious Diseases, University of Heidelberg Medical School, Heidelberg, Germany.
Jessica KehrerParasitology, Department of Infectious Diseases, University of Heidelberg Medical School, Heidelberg, Germany.ORCID 0000-0001-5084-3485
Andreia PintoInstituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, Lisbon, Portugal.
Mário da CostaInstituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, Lisbon, Portugal.
Blandine Franke-FayardLeiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-6041-4182
Chris J JanseLeiden Malaria Research Group, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.
Friedrich FrischknechtParasitology, Department of Infectious Diseases, University of Heidelberg Medical School, Heidelberg, Germany.
Gunnar R MairInstituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Edifício Egas Moniz, Av. Prof. Egas Moniz, Lisbon, Portugal.ORCID 0000-0002-5187-3691
Heidelberg University · DEUniversity of Lisbon · PTLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliding motility allows malaria parasites to migrate and invade tissues and cells in different hosts. It requires parasite surface proteins to provide attachment to host cells and extracellular matrices. Here, we identify the

Indexed as

LocomotionAnimalsCulicidaeDisease Models, AnimalLiverLysosomal Membrane ProteinsMalariaMembrane ProteinsMicePlasmodium bergheiProtozoan ProteinsSporozoitesVirulence FactorsLysosomal Membrane ProteinsMembrane ProteinsProtozoan ProteinsVirulence Factorscell adhesioncell biologygliding motilityinfectious diseasemalariamicrobiologyPlasmodium bergheitransmission

Identifiers

PMID28525314
PMCPMC5438254
OpenAlexW2615587616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.