ReviewAnnual review of neuroscience2017
Mood, the Circadian System, and Melanopsin Retinal Ganglion Cells.
Review in Annual review of neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bidirectional Relationship Between Myopia and Mental Disorders.Depression and anxiety · 2025Pooled it
- Trial
- Divergence of Melanopsin's Intrinsic Properties and Downstream Actions.bioRxiv : the preprint server for biology · 2026Article
- Convergent genetic pathways linking neuropsychiatric and ocular disorders in children.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Histomorphometrical Analyses of the Mouse Suprachiasmatic Nucleus.Bio-protocol · 2026Article
- Minimal Mimics and Maps of Natural Light for Mammals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Light Exposure as a Modifiable Determinant of Mental Health.Current psychiatry reports · 2026Review
- A hypothetical circadian‒endocrine pathway linking melanopsin-expressing ipRGC dysfunction in autoimmune retinopathy to sexual dysfunction.International ophthalmology · 2026Review
- Home lighting, blue-light filtering, and their effects on melatonin suppression.Scientific reports · 2026Article
- The role of circadian rhythms in the pathogenesis of myopia.Frontiers in physiology · 2026Review
- Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review).Molecular medicine reports · 2026Review
- The intersection of circadian rhythms and the blood-brain barrier with drug efficacy and delivery in neurological disorders.Advanced drug delivery reviews · 2025Review
- Review
- Article
- Spatial Mapping of Activity Changes across Sensory Areas Following Visual Deprivation in Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Beyond vision loss: the impact of glaucoma on the brain.Frontiers in cell and developmental biology · 2025Review
- Age-Related Macular Degeneration and Circadian Preference.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Ocular manifestations in autism spectrum disorder.International journal of ophthalmology · 2025Review
- Mapping the Connection Between Circadian Rhythms, Metabolism, and Neurodegeneration: Exploring Therapeutic Strategies.Current Alzheimer research · 2025Review
- Light modulates glucose and lipid homeostasis via the sympathetic nervous system.Science advances · 2024Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The discovery of a third type of photoreceptors in the mammalian retina, intrinsically photosensitive retinal ganglion cells (ipRGCs), has had a revolutionary impact on chronobiology. We can now properly account for numerous non-vision-related functions of light, including its effect on the circadian system. Here, we give an overview of ipRGCs and their function as it relates specifically to mood and biological rhythms. Although circadian disruptions have been traditionally hypothesized to be the mediators of light's effects on mood, here we present an alternative model that dispenses with assumptions of causality between the two phenomena and explains mood regulation by light via another ipRGC-dependent mechanism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.