Evidence map›Paper›PMID 28524157›Full record

ArticleBritish journal of cancer2017

GP participation in increasing uptake in a national bowel cancer screening programme: the PEARL project.

Sally C Benton, Piers Butler, Katy Allen, Michelle Chesters, Sally Rickard, Sally Stanley, Richard Roope, Daniel Vulkan, Stephen W Duffy

Abstract read
In one paragraph

Article in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sally C BentonNHS Bowel Cancer Screening Programme Southern Hub, Surrey Pathology Services, 20 Priestley Road, Surrey Research Park, Guildford, Surrey, GU2 7YS, UK.
Piers ButlerNHS Bowel Cancer Screening Programme Southern Hub, Surrey Pathology Services, 20 Priestley Road, Surrey Research Park, Guildford, Surrey, GU2 7YS, UK.
Katy AllenNHS Bowel Cancer Screening Programme Southern Hub, Surrey Pathology Services, 20 Priestley Road, Surrey Research Park, Guildford, Surrey, GU2 7YS, UK.
Michelle ChestersWessex Cancer Clinical Network, Oakley Road, Southampton, Hampshire SO16 4GX, UK.
Sally RickardThe Whiteley Surgery, Yew Tree Drive, Whiteley, Fareham PO15 7LB, UK.
Sally StanleyThe Whiteley Surgery, Yew Tree Drive, Whiteley, Fareham PO15 7LB, UK.
Richard RoopeThe Whiteley Surgery, Yew Tree Drive, Whiteley, Fareham PO15 7LB, UK.
Daniel VulkanCentre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK.
Stephen W DuffyCentre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe NHS Bowel Cancer Screening Programme (BCSP) in England does not involve general practitioners (GPs). Uptake is ∼58%. The Practice Endorsed Additional Reminder Letter (PEARL) study piloted a GP-endorsed reminder letter.

methodsGeneral practices in Wessex with uptake <55% (prevalent invitations) were invited to participate. Subjects who had been invited for screening, sent a standard 28-day BCSP reminder letter but had not returned a test kit within 30 days of the standard reminder were sent a second reminder letter bearing the GP's letterhead and signature. Uptake was compared between PEARL and non-PEARL practices by standardised uptake ratio (standardised for prior prevalent uptake and other confounders). In addition, 25 non-PEARL practices were matched with PEARL practices for prior prevalent uptake and number of invitees.

resultsTwenty-five practices agreed to participate. A total of 3149 GP-endorsed reminders were sent. Uptake in the PEARL practices was 54% compared with 51% in the matched-control practices. The adjusted RR for uptake was 1.08 (95% CI: 1.05, 1.11, P<0.001) for all invitees and 2.18 (1.79, 2.66, P<0.001) for invitees who had not returned a kit following the standard reminder.

conclusionsThe GP-endorsed reminder was associated with significantly increased uptake among subjects not responding to the standard reminder letter.

Indexed as

Occult BloodPhysician's RoleAgedColorectal NeoplasmsEarly Detection of CancerEnglandFemaleGeneral PracticeHumansMaleMiddle AgedPatient Acceptance of Health CarePilot ProjectsReminder Systems

Identifiers

PMID28524157
PMCPMC5518858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.