ArticleAnnals of intensive care2017
External validation of SAPS 3 and MPM
Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Performance of critical care prognostic scoring systems in low and middle-income countries: a systematic review.Critical care (London, England) · 2018Pooled it
- Association between prolonged Emergency Department stay and Intensive Care Unit mortality among patients at a tertiary hospital in Ethiopia.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Development and pilot testing of the AMPS model for predicting ICU mortality in low and middle income countries.Scientific reports · 2026Article
- The customization of general outcome prediction models: a statistical exercise or a necessity?Critical care science · 2026Article
- Contemporary validation of a SAPS 3 customized version in patients admitted to Brazilian and Uruguayan intensive care units: a multicenter cohort study.Critical care science · 2026Observational
- External Validation of the Simplified Acute Physiology Score-3 in a Cohort of 5,033 Patients in Mexico.Cureus · 2026Article
- Evaluating the MPM III and SAPS III prognostic models in a war-affected, resource-limited setting: a prospective study from the Gaza Strip.BMC health services research · 2025Article
- Performance of Pediatric Risk of Mortality IV in Brazilian PICUs: A Multicenter Prospective Study.Critical care explorations · 2025Article
- Update on the Epimed Monitor Adult ICU Database: 15 years of its use in national registries, quality improvement initiatives and clinical research.Critical care science · 2024Review
- Article
- Performance of NUTRIC score to predict 28-day mortality in critically ill patients after replacing APACHE II with SAPS 3.PloS one · 2022Article
- Simplified acute physiology score III is excellent for predicting in-hospital mortality in coronary care unit patients with acute myocardial infarction: A retrospective study.Frontiers in cardiovascular medicine · 2022Article
- Addition of admission lactate levels to Baux score improves mortality prediction in severe burns.Scientific reports · 2021Article
- Article
- The Effect of Support Surfaces on the Incidence of Pressure Injuries in Critically Ill Patients: A Randomized Clinical Trial.Critical care research and practice · 2018Article
- Comparison of SAPS 3 performance in patients with and without solid tumor admitted to an intensive care unit in Brazil: a retrospective cohort study.Revista Brasileira de terapia intensivaArticle
- The Epimed Monitor ICU Database®: a cloud-based national registry for adult intensive care unit patients in Brazil.Revista Brasileira de terapia intensivaArticle
- Infectious complications associated with parenteral nutrition in intensive care unit and non-intensive care unit patients.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
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Authors and funding
21 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe performance of severity-of-illness scores varies in different scenarios and must be validated prior of being used in a specific settings and geographic regions. Moreover, models' calibration may deteriorate overtime and performance of such instruments should be reassessed regularly. Therefore, we aimed at to validate the SAPS 3 in a large contemporary cohort of patients admitted to Brazilian ICUs. In addition, we also compared the performance of the SAPS 3 with the MPM
methodsThis is a retrospective cohort study in which 48,816 (medical admissions = 67.9%) adult patients are admitted to 72 Brazilian ICUs during 2013. We evaluated models' discrimination using the area under the receiver operating characteristic curve (AUROC). We applied the calibration belt to evaluate the agreement between observed and expected mortality rates (calibration).
resultsMean SAPS 3 score was 44.3 ± 15.4 points. ICU and hospital mortality rates were 11.0 and 16.5%. We estimated predicted mortality using both standard (SE) and Central and South American (CSA) customized equations. Predicted mortality rates were 16.4 ± 19.3% (SAPS 3-SE), 21.7 ± 23.2% (SAPS 3-CSA) and 14.3 ± 14.0% (MPM
conclusionsIn a large contemporary database, the SAPS 3-SE was accurate in predicting outcomes, supporting its use for performance evaluation and benchmarking in Brazilian ICUs.
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