Evidence map›Paper›PMID 28523402›Full record

ReviewJournal of clinical immunology2017

Advances in the Care of Primary Immunodeficiencies (PIDs): from Birth to Adulthood.

Nizar Mahlaoui, Klaus Warnatz, Alison Jones, Sarita Workman, Andrew Cant

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Inborn Errors of Immunity: New Insights.Acta medica academica · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Monitoring patients with uncomplicated common variable immunodeficiency: a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Nizar MahlaouiFrench National Reference Center for Primary Immune Deficiencies (CEREDIH), Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. nizar.mahlaoui@aphp.fr.ORCID http://orcid.org/0000-0002-0030-8094
Klaus WarnatzCenter for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Alison JonesImmunology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Sarita WorkmanDepartment of Immunology, Royal Free London NHS Foundation Trust, 2nd Floor, Pond Street, Hampstead, London, NW3 2QG, UK.
Andrew CantGreat North Children's Hospital, & Institute for Cellular Medicine University of Newcastle, Newcastle upon Tyne, NE4 1LP, UK.
Délégation Paris 5 · FRGreat North Children's Hospital · GBGreat Ormond Street Hospital for Children NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary immunodeficiencies (PIDs) are a widely heterogeneous group of inherited defects of the immune system consisting of many clinical phenotypes with at least 300 underlying genetic deficits currently known. Patients with PIDs can present with, or develop during the course of their life, a susceptibility to recurrent and chronic infection along with autoimmune, allergic, inflammatory, and/or proliferative disorders, all potentially leading to end-organ damage. In recent years, a combination of basic and clinical research has greatly improved understanding of the underlying immunological and genetic defects in PIDs, leading to improved diagnosis, classification, and treatment approaches. In this review, we consider some of the key understandings that should direct diagnostic and treatment approaches in PID and offer insights into current and emerging management approaches and the lifelong care of patients from childhood through to adulthood.

Indexed as

AdolescentAdultAge FactorsChildChild, PreschoolDelivery of Health CareDisease ManagementHumansImmunologic Deficiency SyndromesInfantInfant, NewbornYoung Adultcontinuity of carediagnosismanagementPrimary immunodeficiencyreference centers/networksteenagerstransfer clinictransition careyoung adults

Identifiers

PMID28523402
PMCPMC5489581
OpenAlexW2616450461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.