ArticleInternational urogynecology journal2018
Long-term effect of thermoablative fractional CO
Article in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of C02 Microfractionated Laser in Conjunction With Topical Regenerative Therapy in the Management of Vulvo-vaginal Atrophy in Patients With a History of Breast Cancer. Randomized Experimental and Comparative Study.
Effects of Tanzberger Versus Pelvic Floor Muscle Training on Urinary Incontinence and Quality of Life in post_menopausal Females
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- The efficacy of COLasers in medical science · 2023Pooled it
- The use of vaginal lasers in the treatment of urinary incontinence and overactive bladder, systematic review.International urogynecology journal · 2021Pooled it
- Intravaginal energy-based devices and sexual health of female cancer survivors: a systematic review and meta-analysis.Lasers in medical science · 2020Pooled it
- A systematic review on vaginal laser therapy for treating stress urinary incontinence: Do we have enough evidence?International urogynecology journal · 2017Pooled it
- A Randomized Controlled Trial of Platelet-Rich Plasma Combined with Fractional COInternational urogynecology journal · 2026Trial
- Vaginal Laser Treatment on Stress Urinary Incontinence: A Randomized Controlled Trial.International urogynecology journal · 2025Trial
- How Long Does Urinary Continence Last After Treatment with Intravaginal COInternational urogynecology journal · 2025Trial
- Is the Addition of COMedicina (Kaunas, Lithuania) · 2025Trial
- Fractional COInternational urogynecology journal · 2023Trial
- The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial.International urogynecology journal · 2022Trial
- Vaginal erbium laser for treatment of stress urinary incontinence: optimization of treatment regimen for a sustained long-term effect.Lasers in medical science · 2022Trial
- The Long-Term Effectiveness of Fractional COInternational urogynecology journal · 2026Article
- Modern methods of treating vaginal dryness and atrophy.Przeglad menopauzalny = Menopause review · 2026Review
- Vaginal Laser Therapy as a Potential Treatment Option for Postmenopausal Women With Recurrent Cystitis: Initial Experience From a Single Institution.Lasers in surgery and medicine · 2025Article
- Effect of lattice COWorld journal of psychiatry · 2025Article
- Thermo-Ablative Fractional COMedical sciences (Basel, Switzerland) · 2025Article
- Predictors of the efficacy of CO 2 laser therapy for female stress urinary incontinence.Journal of the Chinese Medical Association : JCMA · 2025Article
- Assessing the Long-Term Effectiveness of Fractional COJournal of clinical medicine · 2025Article
- Current Treatment of Stress Urinary Incontinence by Bulking Agents and Laser Therapy-An Update.Journal of clinical medicine · 2024Review
- Vaginal COBMC cancer · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe aim of this study was to evaluate the long-term effect of thermoablative fractional CO
methodsA total of 161 postmenopausal patients (age 53.38 ± 5.1 years, range 45-65 years) with a clinical diagnosis of mild SUI were prospectively enrolled in the study. Patients received one treatment with TACO2L every 30-45 days, each treatment comprising four sessions, followed in all patients by a yearly treatment session at 12, 24 and 36 months. SUI was evaluated using the International Continence Society 1-h pad test and the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) before and after TACO2L treatment.
resultsTACO2L treatment was associated with a significant improvement in ICIQ-UI SF scores and 1-h pad weight test at 12 months (both p < 0.001), 24 months (both p < 0.001) and 36 months (both p < 0.001). Improvements were maintained for up to 36 months without the need for any further intervention. The results were confirmed by significant histological changes related to trophic restoration of the vagina, responsible for extrinsic and intrinsic mechanisms involved in urinary continence.
conclusionsOur results suggest that TACO2L is an efficient and safe novel treatment strategy in patients with mild SUI. Further investigation to confirm the long-term results presented here is still warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.