Evidence map›Paper›PMID 28523215›Full record

ArticleBrain and behavior2017

Migraine prevalence in patients with unruptured intracranial aneurysms: A case-control study.

Elbert H Witvoet, Nadine Pelzer, Gisela M Terwindt, Gabriël J E Rinkel, Monique H M Vlak, Ale Algra, Marieke J H Wermer

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Appropriateness of magnetic resonance angiography in the evaluation of migraine patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  12. Migraine and risk of stroke.Journal of neurology, neurosurgery, and psychiatry · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elbert H WitvoetDepartment of Neurology Leiden University Medical Center Leiden The Netherlands.ORCID 0000-0002-9973-5159
Nadine PelzerDepartment of Neurology Leiden University Medical Center Leiden The Netherlands.
Gisela M TerwindtDepartment of Neurology Leiden University Medical Center Leiden The Netherlands.
Gabriël J E RinkelDepartment of Neurology and Neurosurgery Brain Center Rudolf Magnus University Medical Center Utrecht Utrecht The Netherlands.
Monique H M VlakDepartment of Neurology Haaglanden Medical Center The Hague The Netherlands.
Ale AlgraDepartment of Neurology and Neurosurgery Brain Center Rudolf Magnus University Medical Center Utrecht Utrecht The Netherlands.
Marieke J H WermerDepartment of Neurology Leiden University Medical Center Leiden The Netherlands.
Leiden University Medical Center · NLMedisch Centrum Haaglanden · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMigraine is a suggested risk factor for aneurysmal subarachnoid hemorrhage (aSAH). An increased risk of aSAH in migraineurs may be explained by an increased prevalence of unruptured intracranial aneurysms (UIA). We performed a case-control study to compare lifetime migraine prevalence in patients with UIA, patients with a history of transient ischemic attact (TIA) or ischemic stroke and controls without a history of aSAH, TIA or ischemic stroke. MATERIALS AND

methodsPatients with UIA were recruited from two university hospitals. Data on patients with TIA/stroke were retrieved from a previous study. Partners of patients with UIA or TIA/stroke were included as controls. Migraine history was assessed via a telephone interview based on the International Classification of Headache Disorders, second edition criteria. We calculated odds ratios (OR) for migraine with univariable and multivariable logistic regression analyses, adjusted for age, sex, hypertension and smoking.

resultsWe included 172 patients with UIA, 221 patients with TIA or stroke, and 164 controls. In UIA patients, migraine prevalence was 24.4% compared with 14.6% in controls (UIA vs. controls; OR 1.9; 95% confidence interval [CI] 1.1-3.5) and 22.2% in TIA/stroke patients (UIA vs. TIA/stroke; OR 1.1; 95% CI 0.7-1.8). After adjustments, the OR for migraine in UIA patients versus controls were 1.7 (95% CI 1.0-3.1) and 0.9 (95% CI 0.5-1.0) versus TIA/stroke. Results were comparable for migraine with and without aura.

conclusionsMigraine prevalence is possibly increased in patients with UIA compared with controls and comparable with the prevalence in patients with TIA or stroke. Further studies are needed to confirm our findings and to investigate the underlying pathophysiology.

Indexed as

AgedCase-Control StudiesComorbidityFemaleHumansIntracranial AneurysmMaleMiddle AgedMigraine DisordersNetherlandsPrevalenceProspective StudiesRisk Factorsintracranial aneurysmsmigrainestrokesubarachnoid hemorrhage

Identifiers

PMID28523215
PMCPMC5434178
OpenAlexW2601401238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.