Evidence map›Paper›PMID 28523044›Full record

ArticlePakistan journal of medical sciences

Evaluation of the synergistic effect of a combination of colistin and tigecycline against multidrug-resistant

Ilkem Acar Kaya, Muberra Devrim Guner, Gulcin Akca, Semra Tuncbilek, Aslihan Alhan, Emin Tekeli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Successful Treatment of MDRClinical case reports · 2024
    Article
  3. Carbapenem-resistantInfection and drug resistance · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ilkem Acar KayaIlkem Acar Kaya, MD. Infectious Diseases and Clinical Microbiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
Muberra Devrim GunerMuberra Devrim Guner, Associate Professor, TOBB Economics and Technology University, Medical School Medical Pharmacology Department, Ankara, Turkey.
Gulcin AkcaGulcin Akca, Associate Professor, Medical Microbiology Department, Gazi University Faculty of Dentistry, Ankara, Turkey.
Semra TuncbilekProf. Semra Tuncbilek, Medical School Infectious Diseases and Clinical Microbiology Department, Ufuk University, Ankara, Turkey.
Aslihan AlhanAslihan Alhan, Assistant Professor, Faculty of Arts and Science Statistics Department, Ufuk University, Ankara, Turkey.
Emin TekeliProf. Emin Tekeli, Medical School Infectious Diseases and Clinical Microbiology Department, Ufuk University, Ankara, Turkey.
Ufuk University · TRAnkara Numune Eğitim ve Araştırma Hastanesi · TRGazi University · TRTOBB University of Economics and Technology · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective

methodsWe included 50 MDR

resultsNo tigecycline and colistin resistance was determined by BMD or E-test. The interaction between colistin and tigecycline, when used in combination, was 2% synergistic, 6% additive, 88% indifferent, and 4% antagonistic.

conclusionAlthough combination therapy is suggested for MDR

Indexed as

Acinetobacter baumanniiColistinMultidrug resistanceSynergyTigecycline

Identifiers

PMID28523044
PMCPMC5432711
OpenAlexW2607495285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.