Evidence map›Paper›PMID 28523000›Full record

ArticleFrontiers in immunology2017

Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction.

Maguelonne Pons, Liza Ali, Walid Beghdadi, Luca Danelli, Marianne Alison, Lydia Celia Madjène, Jessica Calvo, Julien Claver, Shamila Vibhushan, Magnus Åbrink and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Mast Cell Chymase and Kidney Disease.International journal of molecular sciences · 2020
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Maguelonne PonsINSERM UMRS 1149, Paris, France.
Liza AliINSERM UMRS 1149, Paris, France.
Walid BeghdadiINSERM UMRS 1149, Paris, France.
Luca DanelliCNRS ERL8252, Paris, France.
Marianne AlisonDepartment of Pediatric Radiology, Hôpital Robert Debré, APHP, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Lydia Celia MadjèneINSERM UMRS 1149, Paris, France.
Jessica CalvoDepartment of Pathology, Hôpital Robert Debré, APHP, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Julien ClaverINSERM UMRS 1149, Paris, France.
Shamila VibhushanINSERM UMRS 1149, Paris, France.
Magnus ÅbrinkSection of Immunology, Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Gunnar PejlerUppsala University, Department of Medical Biochemistry and Microbiology, Uppsala, Sweden.
Marie-Laurence Poli-MérolPediatric Surgery Unit, American Memorial Hospital, Université Reims Champagne Ardennes, Reims, France.
Michel PeuchmaurDepartment of Pathology, Hôpital Robert Debré, APHP, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Alaa El GhoneimiINSERM UMRS 1149, Paris, France.
Ulrich BlankINSERM UMRS 1149, Paris, France.
Sorbonne Paris Cité · FRDélégation Paris 7 · FRCentre National de la Recherche Scientifique · FRSwedish University of Agricultural Sciences · SEHôpital Robert-Debré · FRInserm · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive nephropathy constitutes a major cause of pediatric renal progressive disease. The mechanisms leading to disease progression are still poorly understood. Kidney fibrotic lesions are reproduced using a model of partial unilateral ureteral obstruction (pUUO) in newborn mice. Based on data showing significant mast cell (MC) infiltration in patients, we investigated the role of MC and murine MCPT4, a MC-released chymase, in pUUO using MC- (W

Indexed as

chymasefibrosishydronephrosisinflammationmast cells

Identifiers

PMID28523000
PMCPMC5415561
OpenAlexW2611859458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.