Evidence map›Paper›PMID 28522938›Full record

ArticleJournal of biomedical nanotechnology2016

Mucin-1-Antibody-Conjugated Mesoporous Silica Nanoparticles for Selective Breast Cancer Detection in a Mucin-1 Transgenic Murine Mouse Model.

Didier Dréau, Laura Jeffords Moore, Merlis P Alvarez-Berrios, Mubin Tarannum, Pinku Mukherjee, Juan L Vivero-Escoto

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 65 citations in OpenAlex.

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  15. Exosomes as Actively Targeted Nanocarriers for Cancer Therapy.International journal of nanomedicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Didier DréauDepartment of Biological Sciences, The University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte NC 28223, USA.
Laura Jeffords MooreDepartment of Biological Sciences, The University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte NC 28223, USA.
Merlis P Alvarez-BerriosDepartment of Chemistry, The University of North Carolina at Charlotte, Charlotte NC 28223, USA; 9201 University City Blvd, Charlotte NC 28223, USA.
Mubin TarannumDepartment of Chemistry, The University of North Carolina at Charlotte, Charlotte NC 28223, USA; 9201 University City Blvd, Charlotte NC 28223, USA.
Pinku MukherjeeDepartment of Biological Sciences, The University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte NC 28223, USA.
Juan L Vivero-EscotoDepartment of Chemistry, The University of North Carolina at Charlotte, Charlotte NC 28223, USA; 9201 University City Blvd, Charlotte NC 28223, USA.
University of North Carolina at Charlotte · US

Funding

Multifunctional nanoparticles for combinational therapy of pancreatic cancerR15CA192160 · NCI · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI VIVERO-ESCOTO, JUAN LUIS · 2015 to 2015
$437k
NCI NIH HHS R15 CA192160
6 · The paper itself

Abstract

Mucin-1 (MUC1), a transmembrane glycoprotein is aberrantly expressed on ~90% of breast cancer and is an excellent target for nanoparticulate targeted imaging. In this study, the development of a dye-doped NIR emitting mesoporous silica nanoparticles platform conjugated to tumor-specific MUC1 antibody (ab-tMUC1-NIR-MSN) for

Indexed as

NanoparticlesSilicon DioxideAnimalsBreast NeoplasmsDisease Models, AnimalFemaleHumansMammary Neoplasms, ExperimentalMiceMice, Inbred C57BLMice, TransgenicMucin-1Mucin-1Silicon DioxideBreast CancerDiagnosisMesoporous Silica NanoparticlesMucin-1Transgenic Mouse Model

Identifiers

PMID28522938
PMCPMC5431076
OpenAlexW2549024233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.