Evidence map›Paper›PMID 28522910›Full record

ArticleWorld journal of gastroenterology2017

Comparison of the analgesic effects between electro-acupuncture and moxibustion with visceral hypersensitivity rats in irritable bowel syndrome.

Ji-Meng Zhao, Liang Li, Liu Chen, Yin Shi, Yu-Wei Li, Hai-Xia Shang, Lu-Yi Wu, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ji-Meng ZhaoJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Liang LiJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Liu ChenJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Yin ShiJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Yu-Wei LiJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Hai-Xia ShangJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Lu-Yi WuJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Zhi-Jun WengJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Chun-Hui BaoJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Huan-Gan WuJi-Meng Zhao, Yin Shi, Zhi-Jun Weng, Chun-Hui Bao, Huan-Gan Wu, Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNCreative Research Enterprises (United States) · USShanghai Research Center for Acupuncture and Meridians · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo observe whether there are differences in the effects of electro-acupuncture (EA) and moxibustion (Mox) in rats with visceral hypersensitivity.

methodsEA at 1 mA and 3 mA and Mox at 43 °C and 46 °C were applied to the Shangjuxu (ST37, bilateral) acupoints in model rats with visceral hypersensitivity. Responses of wide dynamic range neurons in dorsal horns of the spinal cord were observed through the extracellular recordings. Mast cells (MC) activity in the colons of rats were assessed, and 5-hydroxytryptamine (5-HT), 5-hydroxytryptamine 3 receptor (5-HT3R) and 5-HT4R expressions in the colons were measured.

resultsCompared with normal control group, responses of wide dynamic range neurons in the dorsal horn of the spinal cord were increased in the EA at 1 mA and 3 mA groups (1 mA: 0.84 ± 0.74

conclusionThe analgesic effects of Mox at 46 °C are greater than those of Mox at 43 °C, EA 1 mA and EA 3 mA.

Indexed as

ElectroacupunctureMoxibustionAbdominal PainAnimalsColonDisease Models, AnimalHyperalgesiaIrritable Bowel SyndromeMaleMast CellsPain ManagementPain MeasurementPosterior Horn CellsRats, Sprague-DawleyReceptors, Serotonin, 5-HT3Receptors, Serotonin, 5-HT4Receptors, Serotonin, 5-HT3Receptors, Serotonin, 5-HT4SerotoninAnalgesic effectElectro-acupunctureMoxibustionRatsVisceral hypersensitivity

Identifiers

PMID28522910
PMCPMC5413787
OpenAlexW2608648177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.