Evidence map›Paper›PMID 28522907›Full record

ArticleWorld journal of gastroenterology2017

Droplet digital PCR for quantification of

Elizabeth Herring, Shigeru Kanaoka, Éric Tremblay, Jean-François Beaulieu

Open access · hybridAbstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Colorectal Cancer: Risk Factors, Novel Approaches in Molecular Screening and Treatment.International journal of molecular and cellular medicine · 2025
    Review
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  9. IntegrinJournal of oncology · 2022
    Article
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  16. Detection ofWorld journal of gastroenterology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elizabeth HerringElizabeth Herring, Éric Tremblay, Jean-François Beaulieu, Laboratory of Intestinal Physiopathology, Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H5N4, Canada.
Shigeru KanaokaElizabeth Herring, Éric Tremblay, Jean-François Beaulieu, Laboratory of Intestinal Physiopathology, Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H5N4, Canada.
Éric TremblayElizabeth Herring, Éric Tremblay, Jean-François Beaulieu, Laboratory of Intestinal Physiopathology, Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H5N4, Canada.
Jean-François BeaulieuElizabeth Herring, Éric Tremblay, Jean-François Beaulieu, Laboratory of Intestinal Physiopathology, Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H5N4, Canada.
Université de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the use of droplet digital polymerase chain reaction (ddPCR) for detecting host mRNA markers in stools as a non-invasive test for colorectal cancer screening.

methodsddPCR and quantitative PCR were compared side by side for their performance in the detection of

resultsWe found that the ddPCR and qPCR methods performed equally well in this TaqMan duplex assay for the detection of

conclusionWe found that

Indexed as

AdenomaArea Under CurveBiomarkers, TumorCase-Control StudiesColorectal NeoplasmsFecesHumansIntegrin alpha6Neoplasm StagingPolymerase Chain ReactionPredictive Value of TestsReproducibility of ResultsRNA, MessengerRNA, NeoplasmROC CurveBiomarkers, TumorIntegrin alpha6ITGA6 protein, humanRNA, MessengerRNA, NeoplasmAdvanced adenomaBiomarkerColorectal cancermRNANon-invasive screening

Identifiers

PMID28522907
PMCPMC5413784
OpenAlexW2607624147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.