Evidence map›Paper›PMID 28522847›Full record

ArticleScientific reports2017

A Molecular Basis for Selective Antagonist Destabilization of Dopamine D

Sara Marsango, Gianluigi Caltabiano, Mireia Jiménez-Rosés, Mark J Millan, John D Pediani, Richard J Ward, Graeme Milligan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. The MProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. GPCR homo-oligomerization.Current opinion in cell biology · 2019
    Review
  10. Review
  11. Muscarinic receptor oligomerization.Neuropharmacology · 2018
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Sara MarsangoCentre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK. sara.marsango@glasgow.ac.uk.
Gianluigi CaltabianoLaboratori de Medicina Computacional, Unitat de Bioestadística, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Mireia Jiménez-RosésLaboratori de Medicina Computacional, Unitat de Bioestadística, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Mark J MillanInstitut de Recherches Servier, Centre for Innovation in Neuropsychiatry, 125 Chemin de Ronde, Croissy sur Seine, France, 78290.
John D PedianiCentre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK.
Richard J WardCentre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK.
Graeme MilliganCentre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK. Graeme.Milligan@glasgow.ac.uk.
University of Glasgow · GBUniversitat Autònoma de Barcelona · ESPlateforme Technologique d'Innovation Biomédicale · FR

Funding

Medical Research Council MR/L023806/1
6 · The paper itself

Abstract

The dopamine D

Indexed as

Protein MultimerizationDopamine AntagonistsHaloperidolHEK293 CellsHumansMolecular Docking SimulationProtein BindingReceptors, Dopamine D3SpiperoneDopamine AntagonistsHaloperidolReceptors, Dopamine D3Spiperone

Identifiers

PMID28522847
PMCPMC5437050
OpenAlexW2612596389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.