Evidence map›Paper›PMID 28522760›Full record

ReviewJournal of applied physiology (Bethesda, Md. : 1985)2017

On the existence of a central respiratory oxygen sensor.

Alexander V Gourine, Gregory D Funk

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Amelioration of sleep-disordered breathing with supplemental oxygen in older adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Trial
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  10. Functional modulation of retrotrapezoid neurons drives fentanyl-induced respiratory depression.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Alexander V GourineCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology & Pharmacology, University College London, London, United Kingdom; and a.gourine@ucl.ac.uk.
Gregory D FunkDepartment of Physiology, Women and Children's Health Research Institute, Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada.
University College London · GBWomen and Children’s Health Research Institute · CA

Funding

British Heart Foundation RG/14/4/30736Wellcome Trust 095064Wellcome Trust 200893Wellcome Trust 200893/Z/16/Z
6 · The paper itself

Abstract

A commonly held view that dominates both the scientific and educational literature is that in terrestrial mammals the central nervous system lacks a physiological hypoxia sensor capable of triggering increases in lung ventilation in response to decreases in Po

Indexed as

AnimalsBrainCarotid BodyCentral Nervous SystemChemoreceptor CellsDenervationHumansHypoxiaOxygenRespirationOxygenastrocytebrain stemcarotid bodychemosensitivityhypoxiahypoxic ventilatory responseoxygen

Identifiers

PMID28522760
PMCPMC5792097
OpenAlexW2615122283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.