ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Voluntary Control of Epileptiform Spike-Wave Discharges in Awake Rats.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Spike-wave discharges are uncoupled with cognitive outcome in aged Long-Evans rats.Psychopharmacology · 2026Article
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- Absence seizures and sleep-wake abnormalities in a rat model of GRIN2B neurodevelopmental disorder.Epilepsia · 2025Article
- Interruption of rat absence seizures by auditory stimulation.bioRxiv : the preprint server for biology · 2025Article
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- Article
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- Spike-wave discharges in Sprague-Dawley rats reflect precise intra- and interhemispheric synchronization of somatosensory cortex.Journal of neurophysiology · 2022Article
- Background suppression of electrical activity is a potential biomarker of subsequent brain injury in a rat model of neonatal hypoxia-ischemia.Journal of neurophysiology · 2022Article
- Article
- Article
- Cortical low-frequency power correlates with behavioral impairment in animal model of focal limbic seizures.Epilepsia · 2021Article
- Article
- The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles.Frontiers in neurology · 2021Article
- Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures.Brain : a journal of neurology · 2020Review
- A deletion in Eml1 leads to bilateral subcortical heterotopia in the tish rat.Neurobiology of disease · 2020Article
- Establishing Drug Effects on Electrocorticographic Activity in a Genetic Absence Epilepsy Model: Advances and Pitfalls.Frontiers in pharmacology · 2020Review
- Spontaneous Recurrent Absence Seizure-like Events in Wild-Caught Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Modelling traumatic brain injury and posttraumatic epilepsy in rodents.Neurobiology of disease · 2019Review
- Electrographic spikes are common in wildtype mice.Epilepsy & behavior : E&B · 2018Article
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6 authors at 3 institutions in 1 country.
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Abstract
Genetically inherited absence epilepsy in humans is typically characterized by brief (seconds) spontaneous seizures, which involve spike-wave discharges (SWDs) in the EEG and interruption of consciousness and ongoing behavior. Genetic (inbred) models of this disorder in rats have been used to examine mechanisms, comorbidities, and antiabsence drugs. SWDs have also been proposed as models of complex partial seizures (CPSs) following traumatic brain injury (post-traumatic epilepsy). However, the ictal characteristics of these rat models, including SWDs and associated immobility, are also prevalent in healthy outbred laboratory rats. We therefore hypothesized that SWDs are not always associated with classically defined absence seizures or CPSs. To test this hypothesis, we used operant conditioning in male rats to determine whether outbred strains, Sprague Dawley and Long-Evans, and/or the inbred
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