Evidence map›Paper›PMID 28522673›Full record

ArticleJournal of the American Heart Association2017

Systolic Blood Pressure Within 24 Hours After Thrombectomy for Acute Ischemic Stroke Correlates With Outcome.

Eva A Mistry, Akshitkumar M Mistry, Mohammad Obadah Nakawah, Nicolas K Khattar, Enzo M Fortuny, Aurora S Cruz, Michael T Froehler, Rohan V Chitale, Robert F James, Matthew R Fusco and 1 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 8 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 8 syntheses or guidelines pooled it, 154 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eva A MistryDepartment of Neurology, Houston Methodist Neurological Institute, Houston, TX esamin87@gmail.com.
Akshitkumar M MistryDepartment of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN.
Mohammad Obadah NakawahDepartment of Neurology, Houston Methodist Neurological Institute, Houston, TX.
Nicolas K KhattarDepartment of Neurosurgery, University of Louisville School of Medicine, Louisville, KY.
Enzo M FortunyDepartment of Neurosurgery, University of Louisville School of Medicine, Louisville, KY.
Aurora S CruzDepartment of Neurosurgery, University of Louisville School of Medicine, Louisville, KY.
Michael T FroehlerCerebrovascular Program, Vanderbilt University Medical Center, Nashville, TN.
Rohan V ChitaleDepartment of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN.
Robert F JamesDepartment of Neurosurgery, University of Louisville School of Medicine, Louisville, KY.
Matthew R FuscoDepartment of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN.
John J VolpiDepartment of Neurology, Houston Methodist Neurological Institute, Houston, TX.
University of Louisville · USVanderbilt University Medical Center · USHouston Methodist · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent guidelines suggest treating blood pressure above 180/105 mm Hg during the first 24 hours in patients with acute ischemic stroke undergoing any form of recanalization therapy. Currently, no studies exist to guide blood pressure management in patients with stroke treated specifically with mechanical thrombectomy. We aimed to determine the association between blood pressure parameters within the first 24 hours after mechanical thrombectomy and patient outcomes. METHODS AND

resultsWe retrospectively studied a consecutive sample of adult patients who underwent mechanical thrombectomy for acute ischemic stroke of the anterior cerebral circulation at 3 institutions from March 2015 to October 2016. We collected the values of maximum, minimum, and average values of systolic blood pressure, diastolic blood pressure, and mean arterial pressures in the first 24 hours after mechanical thrombectomy. Primary and secondary outcomes were patients' functional status at 90 days measured on the modified Rankin scale and the incidence and severity of intracranial hemorrhages within 48 hours. Associations were explored using an ordered multivariable logistic regression analyses. A total of 228 patients were included (mean age 65.8±14.3; 104 males, 45.6%). Maximum systolic blood pressure independently correlated with a worse 90-day modified Rankin scale and hemorrhagic complications within 48 hours (adjusted odds ratio=1.02 [1.01-1.03],

conclusionsHigher peak values of systolic blood pressure independently correlated with worse 90-day modified Rankin scale and a higher rate of hemorrhagic complications. Further prospective studies are warranted to identify whether systolic blood pressure is a therapeutic target to improve outcomes.

Indexed as

Blood PressureThrombectomyAgedAged, 80 and overBrain IschemiaDatabases, FactualDisability EvaluationFemaleHumansIntracranial HemorrhagesLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioRetrospective Studiesblood pressurehemorrhageoutcomestrokethrombectomy

Identifiers

PMID28522673
PMCPMC5524120
OpenAlexW2616135419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.