Evidence map›Paper›PMID 28522546›Full record

ArticleThe Plant cell2017

The RxLR Motif of the Host Targeting Effector AVR3a of

Stephan Wawra, Franziska Trusch, Anja Matena, Kostis Apostolakis, Uwe Linne, Igor Zhukov, Jan Stanek, Wiktor Koźmiński, Ian Davidson, Chris J Secombes and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Deciphering the Molecular Interplay Between RXLR-EncodedInternational journal of molecular sciences · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Dynamics in theBiochemistry · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Identification ofMycobiology · 2024
    Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Stephan WawraAberdeen Oomycete Laboratory, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.
Franziska TruschAberdeen Oomycete Laboratory, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.ORCID http://orcid.org/0000-0003-0608-202X
Anja MatenaStructural and Medicinal Biochemistry, Centre of Medicinal Biotechnology, University of Duisburg-Essen, 45141 Essen, Germany.
Kostis ApostolakisAberdeen Oomycete Laboratory, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.
Uwe LinneCore Facility for Mass Spectrometry and Chemistry, Philipps-Universität Marburg, D-35032 Marburg, Germany.
Igor ZhukovInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID http://orcid.org/0000-0002-9912-1018
Jan StanekBiological and Chemical Research Centre (CENT III), Faculty of Chemistry, University of Warsaw, 02-089 Warsaw, Poland.ORCID http://orcid.org/0000-0003-1660-168X
Wiktor KoźmińskiBiological and Chemical Research Centre (CENT III), Faculty of Chemistry, University of Warsaw, 02-089 Warsaw, Poland.ORCID http://orcid.org/0000-0003-2319-4525
Ian DavidsonProteomics Facility, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.
Chris J SecombesScottish Fish Immunology Research Centre, Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen AB24 2TZ, United Kingdom.ORCID http://orcid.org/0000-0001-8781-176X
Peter BayerStructural and Medicinal Biochemistry, Centre of Medicinal Biotechnology, University of Duisburg-Essen, 45141 Essen, Germany.ORCID http://orcid.org/0000-0003-0435-7202
Pieter van WestAberdeen Oomycete Laboratory, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom p.vanwest@abdn.ac.uk.ORCID http://orcid.org/0000-0002-0767-6017
University of Aberdeen · GBUniversity of Duisburg-Essen · DEUniversity of Warsaw · PLInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PLPhilipps University of Marburg · DE

Funding

Biotechnology and Biological Sciences Research Council BB/G012075/1
6 · The paper itself

Abstract

When plant-pathogenic oomycetes infect their hosts, they employ a large arsenal of effector proteins to establish a successful infection. Some effector proteins are secreted and are destined to be translocated and function inside host cells. The largest group of translocated proteins from oomycetes is the RxLR effectors, defined by their conserved N-terminal Arg-Xaa-Leu-Arg (RxLR) motif. However, the precise role of this motif in the host cell translocation process is unclear. Here, detailed biochemical studies of the RxLR effector AVR3a from the potato pathogen

Indexed as

Amino Acid MotifsFungal ProteinsMass SpectrometryPhytophthora infestansSolanum tuberosumFungal Proteins

Identifiers

PMID28522546
PMCPMC5502441
OpenAlexW2615626975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.