Evidence map›Paper›PMID 28522452›Full record

Trial reportAnnals of the rheumatic diseases2018

Arthroscopic partial meniscectomy versus placebo surgery for a degenerative meniscus tear: a 2-year follow-up of the randomised controlled trial.

Raine Sihvonen, Mika Paavola, Antti Malmivaara, Ari Itälä, Antti Joukainen, Heikki Nurmi, Juha Kalske, Anna Ikonen, Timo Järvelä, Tero A H Järvinen and 18 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Annals of the rheumatic diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 6 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 6 syntheses or guidelines pooled it, 142 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 9 institutions in 1 country.

Raine SihvonenDepartment of Orthopedics and Traumatology, Hatanpää Hospital, Tampere, Finland.
Mika PaavolaDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Antti MalmivaaraCenter for Health and Social Economics, National Institute for Health and Welfare, Helsinki, Finland.
Ari ItäläDepartment of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.
Antti JoukainenDepartment of Orthopedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.
Heikki NurmiDepartment of Orthopedics and Traumatology, Central Finland Central Hospital, Jyväskylä, Finland.
Juha KalskeDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Anna IkonenDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Timo JärveläArthroscopic and Sports Medicine Center Pohjola Sairaala, Helsinki, Finland.
Tero A H JärvinenDepartment of Orthopedics and Traumatology, Tampere University Hospital, Tampere, Finland.
Kari KantoDepartment of Orthopedics and Traumatology, Hatanpää Hospital, Tampere, Finland.
Janne KarhunenDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Jani KnifsundDepartment of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.
Heikki KrögerDepartment of Orthopedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.
Tommi KääriäinenDepartment of Orthopedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.
Janne LehtinenDepartment of Orthopedics and Traumatology, Hatanpää Hospital, Tampere, Finland.
Jukka NyrhinenDepartment of Orthopedics and Traumatology, Central Finland Central Hospital, Jyväskylä, Finland.
Juha PalonevaDepartment of Orthopedics and Traumatology, Central Finland Central Hospital, Jyväskylä, Finland.
Outi PäiväniemiDepartment of Orthopedics and Traumatology, Hatanpää Hospital, Tampere, Finland.
Marko RaivioDepartment of Orthopedics and Traumatology, Hatanpää Hospital, Tampere, Finland.
Janne SahlmanDepartment of Orthopedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.
Roope SarvilinnaDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Sikri TukiainenDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Ville-Valtteri VälimäkiDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Ville ÄärimaaDepartment of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.
Pirjo ToivonenDepartment of Orthopaedics and Traumatology, Helsinki University, Töölö Hospital, Helsinki, Finland.
Teppo L N JärvinenDepartment of Orthopaedics and Traumatology, Helsinki University, Töölö Hospital, Helsinki, Finland.
FIDELITY (Finnish Degenerative Meniscal Lesion Study) Investigators
Helsinki University Hospital · FICentral Finland Health Care District · FIKuopio University Hospital · FITampere University Hospital · FITurku University Hospital · FIHatanpää Hospital · FIFinnish Institute for Health and Welfare · FINorthern Ostrobothnia Hospital District · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess if arthroscopic partial meniscectomy (APM) is superior to placebo surgery in the treatment of patients with degenerative tear of the medial meniscus.

methodsIn this multicentre, randomised, participant-blinded and outcome assessor-blinded, placebo-surgery controlled trial, 146 adults, aged 35-65 years, with knee symptoms consistent with degenerative medial meniscus tear and no knee osteoarthritis were randomised to APM or placebo surgery. The primary outcome was the between-group difference in the change from baseline in the Western Ontario Meniscal Evaluation Tool (WOMET) and Lysholm knee scores and knee pain after exercise at 24 months after surgery. Secondary outcomes included the frequency of unblinding of the treatment-group allocation, participants' satisfaction, impression of change, return to normal activities, the incidence of serious adverse events and the presence of meniscal symptoms in clinical examination. Two subgroup analyses, assessing the outcome on those with mechanical symptoms and those with unstable meniscus tears, were also carried out.

resultsIn the intention-to-treat analysis, there were no significant between-group differences in the mean changes from baseline to 24 months in WOMET score: 27.3 in the APM group as compared with 31.6 in the placebo-surgery group (between-group difference, -4.3; 95% CI, -11.3 to 2.6); Lysholm knee score: 23.1 and 26.3, respectively (-3.2; -8.9 to 2.4) or knee pain after exercise, 3.5 and 3.9, respectively (-0.4; -1.3 to 0.5). There were no statistically significant differences between the two groups in any of the secondary outcomes or within the analysed subgroups.

conclusionsIn this 2-year follow-up of patients without knee osteoarthritis but with symptoms of a degenerative medial meniscus tear, the outcomes after APM were no better than those after placebo surgery. No evidence could be found to support the prevailing ideas that patients with presence of mechanical symptoms or certain meniscus tear characteristics or those who have failed initial conservative treatment are more likely to benefit from APM.

Indexed as

AdultAgedArthroscopyFemaleFinlandFollow-Up StudiesHumansIntention to Treat AnalysisMaleMeniscectomyMenisci, TibialMiddle AgedPatient SatisfactionPostoperative ComplicationsRecovery of FunctionTibial Meniscus Injuriesknee osteoarthritisorthopaedic surgerytreatment

Identifiers

PMID28522452
PMCPMC5867417
OpenAlexW2616087671

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.