Evidence map›Paper›PMID 28522083›Full record

ArticleSleep medicine2017

Relationships between potentially traumatic events, sleep disturbances, and symptoms of PTSD and alcohol use disorder in a young adult sample.

Mackenzie J Lind, Allison Baylor, Cassie M Overstreet, Sage E Hawn, Bruce D Rybarczyk, Kenneth S Kendler, Danielle M Dick, Ananda B Amstadter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Fear of Sleep in Undergraduates with a History of Sexual Trauma.Behavioral sciences (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mackenzie J LindDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298-0126, USA. Electronic address: lindmj@vcu.edu.
Allison BaylorDepartment of Psychology, Virginia Commonwealth University, 806 W. Franklin Street, PO Box 842018, Richmond, VA, 23284-2018, USA. Electronic address: abaylor@mymail.vcu.edu.
Cassie M OverstreetDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298-0126, USA; Department of Psychology, Virginia Commonwealth University, 806 W. Franklin Street, PO Box 842018, Richmond, VA, 23284-2018, USA. Electronic address: overstreetcm@mymail.vcu.edu.
Sage E HawnDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298-0126, USA; Department of Psychology, Virginia Commonwealth University, 806 W. Franklin Street, PO Box 842018, Richmond, VA, 23284-2018, USA. Electronic address: hawnse@mymail.vcu.edu.
Bruce D RybarczykDepartment of Psychology, Virginia Commonwealth University, 806 W. Franklin Street, PO Box 842018, Richmond, VA, 23284-2018, USA. Electronic address: bdrybarczyk@vcu.edu.
Kenneth S KendlerDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298-0126, USA; Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980003, Richmond, VA, 23298-0003, USA. Electronic address: kenneth.kendler@vcuhealth.org.
Danielle M DickDepartment of Psychology, Virginia Commonwealth University, 806 W. Franklin Street, PO Box 842018, Richmond, VA, 23284-2018, USA; College Behavioral and Emotional Health Institute, Virginia Commonwealth University, 816 W. Franklin St, PO Box 843092, Richmond, VA, 23284-3092, USA. Electronic address: ddick@vcu.edu.
Ananda B AmstadterDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980126, Richmond, VA, 23298-0126, USA; Department of Human and Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, PO Box 980003, Richmond, VA, 23298-0003, USA. Electronic address: abamstadter@vcu.edu.
Virginia Commonwealth University · US

Funding

Project 5 - Genetic architecture of alcohol use disorder using cross-trait genetic correlations and public next-generation sequencing studiesP50AA022537 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MICHAEL F MILES · 2014 to 2026
$19.6M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
Research Training: Psychiatric &Statistical GeneticsT32MH020030 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI HERMINE H MAES, MICHAEL CHURTON NEALE · 1999 to 2026
$6.7M
An Alcohol Affected Sib Pair Study of Alcohol DependenceR37AA011408 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN · 2007 to 2016
$6.5M
Project 3: Cross Species Characterization of Gene Networks in Acute ResponsesP20AA017828 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI BETTINGER, JILL C · 2009 to 2012
$2.2M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
Stress-induced drinking in Returning Soldiers: Genetic and Epigenetic MechanismsK02AA023239 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI AMSTADTER, ANANDA B · 2014 to 2018
$643k
NCRR NIH HHS UL1 RR031990NIAAA NIH HHS K02 AA018755NIAAA NIH HHS K02 AA023239NIAAA NIH HHS P20 AA017828NIAAA NIH HHS P50 AA022537NIAAA NIH HHS R37 AA011408NIMH NIH HHS T32 MH020030
6 · The paper itself

Abstract

objectiveTraumatic events, particularly those that are interpersonal in nature, are associated with increased risk for co-occurring sequelae, including sleep disturbances, posttraumatic stress disorder (PTSD), and alcohol use disorder (AUD). However, the associations between these phenotypes have not been explored among college students.

methodsWe examined relationships between type of potentially traumatic event (PTE) exposure (pre-college) and sleep disturbances, as well as mediating effects of lifetime PTSD and AUD symptoms on these relationships, in a large undergraduate sample (N = 1599, 64.7% female). Hierarchical linear regressions were conducted, beginning with demographics and then adding interpersonal and accidental PTEs in a stepwise regression; mediation analyses were run.

resultsWithin the sample, 33.7% endorsed at least one interpersonal PTE, while 64.4% endorsed at least one accidental PTE. Hierarchical regressions demonstrated that interpersonal (β = 0.202, p = 0.000), but not accidental PTE exposure significantly predicted disturbed sleep. Both PTSD and AUD symptoms significantly mediated (p values < 0.001) the relationship between interpersonal PTE exposure and sleep, with indirect effects accounting for 61% and 17% of total effects, respectively. In the correlated mediation model, both disorders remained significant mediators (p < 0.001), with indirect effects accounting for 56% (PTSD symptoms) and 14% (AUD symptoms) of total effects on sleep.

conclusionsResults suggest that interpersonal PTEs are more potent predictors of sleep problems than accidental PTEs. Further, trauma exposure psychiatric symptom sequelae (PTSD, AUD) account for part of the relationship between interpersonal PTE exposure and disturbed sleep, which both independently and jointly suggests that treating PTSD and AUD symptoms in college students may also improve sleep.

Indexed as

Life Change EventsAdolescentAlcohol-Related DisordersFemaleHumansLinear ModelsMaleModels, TheoreticalRetrospective StudiesSleep Wake DisordersStress Disorders, Post-TraumaticStudentsUniversitiesYoung AdultAlcohol use disorderCollege studentsPosttraumatic stress disorderPotentially traumatic eventsSleep disturbances

Identifiers

PMID28522083
PMCPMC5695543
OpenAlexW2595539937

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.