Evidence map›Paper›PMID 28521790›Full record

ArticleBMC public health2017

Unintentional drowning: Role of medicinal drugs and alcohol.

Tuulia Pajunen, Erkki Vuori, Frank F Vincenzi, Pirjo Lillsunde, Gordon Smith, Philippe Lunetta

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

  1. Prioritising preventive measures for unintentional sport and recreation-related deaths in Québec, Canada, based on a 14-year review.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. [Drowning mortality in Catalonia (2019-2022)].Revista espanola de salud publica · 2024
    Observational
  6. Hypothesized mechanisms of death in swimming: a systematic review.BMC sports science, medicine & rehabilitation · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Drowning in submerged cars caused by traffic accidents.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
    Article
  13. The link between medical conditions and fatal drownings in Canada: a 10-year cross-sectional analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  14. Article
  15. Article
  16. The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Tuulia PajunenDepartment of Biomedicine, Pathology and Forensic Medicine, University of Turku, Turku, Finland. t09tpaju@utu.fi.ORCID 0000-0002-5001-6604
Erkki VuoriDepartment of Forensic Medicine, University of Helsinki, Helsinki, Finland.
Frank F VincenziDepartment of Pharmacology, University of Washington, Seattle, Washington, USA.
Pirjo LillsundeNational Institute for Health and Welfare, Helsinki, Finland.
Gordon SmithDepartment of Epidemiology and Public Health, University of Maryland, Maryland, USA.
Philippe LunettaDepartment of Biomedicine, Pathology and Forensic Medicine, University of Turku, Turku, Finland.
University of Turku · FIFinnish Institute for Health and Welfare · FIUniversity of Helsinki · FIUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol is a well-known risk factor in unintentional drownings. Whereas psychotropic drugs, like alcohol, may cause psychomotor impairment and affect cognition, no detailed studies have focused on their association with drowning. Finland provides extensive post-mortem toxicological data for studies on drowning because of its high medico-legal autopsy rates.

methodsDrowning cases, 2000 through 2009, for which post-mortem toxicological analysis was performed, came from the database of the Toxicological Laboratory, Department of Forensic Medicine, University of Helsinki, using the ICD-10 nature-of-injury code T75.1. The data were narrowed to unintentional drowning, using the ICD-10 external-injury codes V90, V92, and W65-74. Each drowning case had its blood alcohol concentration (BAC) and concentrations of other drugs recorded. Evaluation of the contribution of psychotropic drugs to drowning was based on their blood concentration by means of a 6-grade scale.

resultsAmong victims ≥15 years old, unintentional drownings numbered 1697, of which, 303 (17.9%) were boating-related and 1394 (82.1%) non-boating-related. Among these, 65.0% of boating-related and 61.8% of non-boating-related victims were alcohol-positive (=BAC ≥ 50 mg/dL). The male-to-female ratio in alcohol-positive drownings was 7.3. At least one psychotropic drug appeared in 453 (26.7%) drowning cases, with some victims' bodies showing up to 7 different drugs. Overall 70 different psychotropic drugs were detectable, with 134 (7.9%) cases both alcohol-negative and psychotropic-drug-positive, of these, 59 (3.5%) were graded 4 to 6, indicating a possible to very probable contribution to drowning. Our findings suggest that psychotropic drugs may play a significant role in drowning, in up to 14.5% of cases, independently or in association with alcohol.

conclusionsPsychotropic drugs alone or in association with alcohol may be an overlooked risk factor in drowning, due to their effects on psychomotor function and cognition. Future studies should also address other mechanisms-for instance drug-induced long-QT syndrome-by which drugs may contribute to drowning.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAlcohol DrinkingAutopsyDrowningEthanolFemaleFinlandForensic MedicineHumansMaleMiddle AgedPsychomotor DisordersEthanolPsychotropic DrugsAlcoholAutopsyPsychotropic drugsUnintentional drowning

Identifiers

PMID28521790
PMCPMC5437510
OpenAlexW2611418876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.