Evidence map›Paper›PMID 28521737›Full record

ArticleBMC cancer2017

Validation of the German version of the Mediterranean Diet Adherence Screener (MEDAS) questionnaire.

Katrin Hebestreit, Maryam Yahiaoui-Doktor, Christoph Engel, Walter Vetter, Michael Siniatchkin, Nicole Erickson, Martin Halle, Marion Kiechle, Stephan C Bischoff

2 registry-linked trialsOpen access · goldAbstract readValidation Study
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02087592 nacompletednot on this map

Prospective Randomized Multicenter Trial to Assess the Feasibility of a Structured Physical Exercise Training and Mediterranean-style Diet in Women With BRCA1/2 Mutations

TypeinterventionalSponsorTechnical University of MunichRan2014 to 2024Enrolled69ConditionsHereditary Breast and Ovarian CancerArmsStructured exercise training plus mediterranean diet
NCT04204239 unknown statusnot on this mapstarted 2020, after this paper: background citation

A Review of Test Procedures From Different Health Care Professions With Regard to Their Suitability for the Early Detection of Cognitive Impairments in Persons Aged 60 and Older: A Validation Study

TypeobservationalSponsorFH Joanneum Gesellschaft mbHRan2020 to 2023Enrolled300ConditionsCognitive Decline, Cognitive Deficit, Cognitive Impairment
3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

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  18. Dietary intervention among young cancer survivors within the CARE for CAYA program.Journal of cancer survivorship : research and practice · 2026
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Katrin HebestreitInstitute for Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70593, Stuttgart, Germany.
Maryam Yahiaoui-DoktorInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.
Christoph EngelInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.
Walter VetterInstitute for Food Chemistry, University of Hohenheim, Fruwirthstr. 12, 70593, Stuttgart, Germany.
Michael SiniatchkinInstitute for Medical Psychology and Sociology, University Hospital Schleswig-Holstein, Campus Kiel, Preusserstr. 1-9, 24105, Kiel, Germany.
Nicole EricksonComprehensive Cancer Center (CCC LMU), Ludwig Maximilian University Munich, Campus Großhadern, Marchioninistr. 15, 81377, Munich, Germany.
Martin HalleElse Kroener-Fresenius Prevention Center, Klinikum rechts der Isar, Technical University Munich (TUM), Ismaningerstr. 22, 81675, Munich, Germany.
Marion KiechleDepartment of Gynecology and Center for Hereditary Breast and Ovarian Cancer, Women's Hospital Klinikum Rechts der Isar der, Technical University Munich (TUM), Gynaecology and Obstetrics, Ismaningerstrasse 22, 81675, Munich, Germany. marion.kiechle@tum.de.
Stephan C BischoffInstitute for Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70593, Stuttgart, Germany.
University of Hohenheim · DELeipzig University · DEFresenius (Germany) · DELudwig-Maximilians-Universität München · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth benefits of the Mediterranean Diet (MD) have been shown in different at-risk populations. A German translation of the Mediterranean Diet Adherence Screener (MEDAS) from the PREvención con DIeta MEDiterránea (PREDIMED) consortium was used in the LIBRE study, investigating effects of lifestyle-intervention on women with BRCA1/2 mutations. The purpose of the present study is to validate the MEDAS German version.

methodsLIBRE is a multicentre (three university hospitals during this pilot phase), unblinded, randomized, controlled clinical trial. Women with a BRCA1/2 mutation of age 18 or over who provided written consent were eligible for the trial. As part of the assessment, all were given a full-length Food Frequency Questionnaire (FFQ) and MEDAS at baseline and after 3 months. Data derived from FFQ was compared to MEDAS in order to evaluate agreement or concordance between the two questionnaires. Additionally, the association of dietary intake biomarkers in the blood (β-carotene, omega-3, omega-6 and omega-9 fatty acids and high-sensitivity C-reactive protein (hsCRP)) with some MEDAS items was analyzed using t-Tests and a multivariate regression.

resultsThe participants of the LIBRE pilot study were 68 in total (33 Intervention, 35 Control). Only participants who completed both questionnaires were included in this analysis (baseline: 66, month three: 54). The concordance between these two questionnaires varied between the items (Intraclass correlation coefficient of 0.91 for pulses at the highest and -0.33 for sugar-sweetened drinks). Mean MEDAS scores (sum of all items) were 9% higher than their FFQ counter-parts at baseline and 15% after 3 months. Higher fish consumption (at least 3 portions) was associated with lower omega-6 fatty acid levels (p = 0.026) and higher omega-3 fatty acid levels (p = 0.037), both results being statistically significant.

conclusionsWe conclude that the German MEDAS in its current version could be a useful tool in clinical trials and in practice to assess adherence to MD.

trial registrationClinicalTrials.gov , registered on March 12, 2014, identifier: NCT02087592 . World Health Organization Trial Registration, registered on 3 August 2015, identifier: NCT02087592 .

Indexed as

AdultAgedBiomarkersBreast NeoplasmsDiet, MediterraneanFeasibility StudiesFemaleGenes, BRCA1Genes, BRCA2GermanyHumansMiddle AgedMutationPilot ProjectsRandomized Controlled Trials as TopicRisk FactorsBiomarkersBRCA1/2Food frequencyHereditary breast cancerMediterranean diet adherenceValidation

Identifiers

PMID28521737
PMCPMC5437541
OpenAlexW2616105403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.