Evidence map›Paper›PMID 28521598›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2018

Malnutrition, Critical Illness Survivors, and Postdischarge Outcomes: A Cohort Study.

Kris M Mogensen, Clare M Horkan, Steven W Purtle, Takuhiro Moromizato, James D Rawn, Malcolm K Robinson, Kenneth B Christopher

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06564168 (Nutritional Status of Critically Ill Diabetic Patients With Type 2 Diabetes Mellitus.), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06564168 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Nutritional Status of Critically Ill Diabetic Patients With Type 2 Diabetes Mellitus.

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled430ConditionsNutrition, Critical Illness, Diabetes Mellitus, Type 2
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 65 citations in OpenAlex.

  1. Nutrition Support in Patients With Delirium: A Retrospective Case Series.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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  5. Exploring Patient Mealtime Experience in an Acute Care Setting Using the Modified Austin Health Patient Mealtime Experience Tool.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kris M MogensenDepartment of Nutrition, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Clare M HorkanDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Steven W PurtleDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Boulder, Colorado, USA.
Takuhiro MoromizatoRenal and Rheumatology Division, Internal Medicine Department, Okinawa Southern Medical Center and Children's Hospital, Naha, Japan.
James D RawnDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Malcolm K RobinsonDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Kenneth B ChristopherThe Nathan E. Hellman Memorial Laboratory, Renal Division, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Brigham and Women's Hospital · USUniversity of Colorado Boulder · US

Funding

Pharmacokinetics and metabolomics of vitamin D supplementation in critical illnessR01GM115774 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI CHRISTOPHER, KENNETH BRUCE · 2016 to 2018
$940k
NIGMS NIH HHS R01 GM115774
6 · The paper itself

Abstract

backgroundWe hypothesized that preexisting malnutrition in patients who survived critical care would be associated with adverse outcomes following hospital discharge.

methodsWe performed an observational cohort study in 1 academic medical center in Boston. We studied 23,575 patients, aged ≥18 years, who received critical care between 2004 and 2011 and survived hospitalization.

resultsThe exposure of interest was malnutrition determined at intensive care unit (ICU) admission by a registered dietitian using clinical judgment and on data related to unintentional weight loss, inadequate nutrient intake, and wasting of muscle mass and/or subcutaneous fat. The primary outcome was 90-day postdischarge mortality. Secondary outcome was unplanned 30-day hospital readmission. Adjusted odds ratios were estimated by logistic regression models adjusted for age, race, sex, Deyo-Charlson Index, surgical ICU, sepsis, and acute organ failure. In the cohort, the absolute risk of 90-day postdischarge mortality was 5.9%, 11.7%, 15.8%, and 21.9% in patients without malnutrition, those at risk of malnutrition, nonspecific malnutrition, and protein-energy malnutrition, respectively. The odds of 90-day postdischarge mortality in patients at risk of malnutrition, nonspecific malnutrition, and protein-energy malnutrition fully adjusted were 1.77 (95% confidence interval [CI], 1.23-2.54), 2.51 (95% CI, 1.36-4.62), and 3.72 (95% CI, 2.16-6.39), respectively, relative to patients without malnutrition. Furthermore, the presence of malnutrition is a significant predictor of the odds of unplanned 30-day hospital readmission.

conclusionsIn patients treated with critical care who survive hospitalization, preexisting malnutrition is a robust predictor of subsequent mortality and unplanned hospital readmission.

Indexed as

SurvivorsAdultAgedCohort StudiesCritical IllnessFemaleHumansIntensive Care UnitsMaleMalnutritionMiddle AgedOdds RatioPatient DischargePatient ReadmissionPrognosisSepsiscritical carehospital readmissionICU survivorsmalnutritionmortalityoutcomes

Identifiers

PMID28521598
PMCPMC5673587
OpenAlexW2615541724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.