Evidence map›Paper›PMID 28521474›Full record

ArticleOncology letters2017

An Ω-3 fatty acid desaturase-expressing gene attenuates prostate cancer proliferation by cell cycle regulation.

Jinshun Pan, Sujin Zhou, Rong Xiang, Zhenggang Zhao, Shanshan Liu, Ning Ding, Sijia Gong, Yan Lin, Xiaoxi Li, Xiaoming Bai and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jinshun PanDepartment of Biotherapy, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Sujin ZhouCollaborative Innovation Center for Cancer Medicine, The Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, P.R. China.
Rong XiangThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Zhenggang ZhaoCollaborative Innovation Center for Cancer Medicine, The Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, P.R. China.
Shanshan LiuThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Ning DingThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Sijia GongThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Yan LinThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Xiaoxi LiThe Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Xiaoming BaiCancer Center, Department of Pathology, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Fanghong LiCollaborative Innovation Center for Cancer Medicine, The Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, P.R. China.
Allan Z ZhaoCollaborative Innovation Center for Cancer Medicine, The Institute of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, P.R. China.
Nanjing Medical University · CNGuangdong University of Technology · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have reported that Ω-6 and Ω-3 fatty acids have opposing effects on cancer development. Consuming high levels of long-chain Ω-3 polyunsaturated fatty acids (PUFAs) has been shown to reduce prostate cancer risk and increase chemotherapy sensitivity. The sdd17 gene encodes an Ω-3 fatty acid desaturase, which converts arachidonic acid into eicosapentaenoic acid (EPA). However, little is known regarding the function of the sdd17 gene in tumor cells

Indexed as

cell cycleE2F1proliferationprostate cancer cellsΩ-3 fatty acid desaturase

Identifiers

PMID28521474
PMCPMC5431302
OpenAlexW2602803153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.