Observational studyJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2017
Surveillance for enterovirus D68 in colorado children reveals continued circulation.
Observational study in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis.PLoS neglected tropical diseases · 2022Pooled it
- Clinical Characteristics of Enterovirus D68 Respiratory Disease in Colorado Children Over a Decade: 2014-2025.The Pediatric infectious disease journal · 2026Article
- Enterovirus D68 B3 clade strains are efficiently recovered from cDNA infectious clones in 293T cells and infect human spinal cord organoids.Journal of virology · 2026Article
- Burden of Disease and Spectrum of Illness From Enterovirus-D68 Infections in US Children 0-2 Years of Age From a Longitudinal Community-Based Cohort, 2017-2019.Journal of the Pediatric Infectious Diseases Society · 2025Article
- Return of the Biennial Circulation of Enterovirus D68 in Colorado Children in 2024 Following the Large 2022 Outbreak.Viruses · 2025Article
- Emerging Therapeutics in the Fight Against EV-D68: A Review of Current Strategies.Influenza and other respiratory viruses · 2024Review
- Enteroviruses: epidemic potential, challenges and opportunities with vaccines.Journal of biomedical science · 2024Review
- Multimodal Surveillance Model for Enterovirus D68 Respiratory Disease and Acute Flaccid Myelitis among Children in Colorado, USA, 2022.Emerging infectious diseases · 2024Review
- Animal Models of Enterovirus D68 Infection and Disease.Journal of virology · 2022Review
- Enterovirus D68-Associated Acute Respiratory Illness ─ New Vaccine Surveillance Network, United States, July-November 2018-2020.MMWR. Morbidity and mortality weekly report · 2021Article
- Acute flaccid myelitis: cause, diagnosis, and management.Lancet (London, England) · 2021Review
- Biennial Upsurge and Molecular Epidemiology of Enterovirus D68 Infection in New York, USA, 2014 to 2018.Journal of clinical microbiology · 2020Article
- Enterovirus D68-associated respiratory infection in southern Brazil, 2018 - A population-based laboratory surveillance.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Article
- Characteristics of Patients with Acute Flaccid Myelitis, United States, 2015-2018.Emerging infectious diseases · 2020Article
- Molecular and Clinical Comparison of Enterovirus D68 Outbreaks among Hospitalized Children, Ohio, USA, 2014 and 2018.Emerging infectious diseases · 2019Article
- Enterovirus D68 Subclade B3 Circulation in Senegal, 2016: Detection from Influenza-like Illness and Acute Flaccid Paralysis Surveillance.Scientific reports · 2019Article
- Review
- Association of Enterovirus D68 with Acute Flaccid Myelitis, Philadelphia, Pennsylvania, USA, 2009-2018.Emerging infectious diseases · 2019Article
- Increase in Enterovirus D68 Infections in Young Children, United Kingdom, 2006-2016.Emerging infectious diseases · 2019Article
- Current Understanding of Human Enterovirus D68.Viruses · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundThe largest, most widespread outbreak of enterovirus D68 respiratory disease occurred from August to December of 2014 in the United States with 1153 confirmed infections in 49 states. The epidemiology of enterovirus D68 following the 2014 outbreak is unknown.
objectivesThis study seeks to describe the epidemiology of enterovirus D68 circulation amongst Colorado children from 2014 to 2016. STUDY
designThis is a prospective observational surveillance study of enterovirus D68 infection amongst children tested for respiratory pathogens from July-October 2014-2016 at Children's Hospital Colorado (CHCO), a quaternary care children's hospital in Aurora, CO.
resultsAmongst rhinovirus/enterovirus positive respiratory specimens from intensive care unit patients, ninety-eight of 314 (31.2%) in 2014, none of 307 (0%) specimens in 2015, and 19 of 240 (7.9%) specimens in 2016 were identified as enterovirus D68. Amongst respiratory specimens from all patients during the prospective active surveillance period, none of 1469 (0%) in 2015 and 46 of 1403 (3.3%) were positive for enterovirus D68.
conclusionsSurveillance for enterovirus D68 amongst respiratory specimens at a quaternary care children's hospital revealed a seasonal pattern of circulation in the late summer to early fall of 2014 and 2016. Continued surveillance of respiratory specimens is necessary to define the circulation pattern and understand the epidemiology of this emerging pathogen.
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