Evidence map›Paper›PMID 28520997›Full record

ReviewJournal of travel medicine2017

Resistant pathogens as causes of traveller's diarrhea globally and impact(s) on treatment failure and recommendations.

David R Tribble

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of travel medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Investigations of the voltage-gated CaFrontiers in pharmacology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. NutriClayJournal of food protection · 2025
    Article
  9. A broadly immunogenic polyvalentInfection and immunity · 2023
    Article
  10. Article
  11. Article
  12. Toward aInternational journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Molecular Detection of Colistin ResistanceAntibiotics (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David R TribbleInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814-5119, USA.
Uniformed Services University of the Health Sciences · US

Funding

NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

background: Diarrhea is a frequent clinical syndrome affecting international travellers. Bacterial etiologic agents have a long history of emergent antimicrobial resistance against commonly used antibiotics. Current approaches applying first-line antimicrobial therapy are being challenged by increasingly resistant organisms. This review summarizes recent epidemiological and clinical evidence of antibiotic resistance among enteropathogens causing traveller's diarrhea and the subsequent impact on current treatment recommendations.

methods: The PubMed database was systemically searched for articles related to antibiotic susceptibility and diarrheal pathogens.

results: Antibiotic resistance related to travellers' diarrhea has increased in recent years. Most notably, fluoroquinolone resistance has expanded from the Campylobacter -associated cases well documented in Southeast Asia in the 1990s to widespread occurrence, as well as increases among other common bacterial enteropathogens including, enterotoxigenic and enteroaggregative Escherichia coli , Shigella and non-typhoidal Salmonella . Multidrug resistance among enteropathogenic Enterobacteriacae and Campylobacter species create further challenges with the selection of empiric therapy. Treatment failures requiring early use of alternative agents, as well as delayed recovery comparable to placebo rates emphasize the impact of antimicrobial resistance on effective treatment.

conclusions: Although there are limitations in the available data, the increasing antibiotic resistance and adverse impact on clinical outcome require continued surveillance and reconsideration of practice guidelines.

Indexed as

Drug Resistance, BacterialTravelAnti-Bacterial AgentsCampylobacterDiarrheaEnterobacteriaceaeEscherichia coliGlobal HealthHumansSalmonellaShigellaAnti-Bacterial Agentsantimicrobial resistanceCampylobacterEnterotoxigenic E. coliSalmonellaShigellaTraveller’s diarrhea

Identifiers

PMID28520997
PMCPMC5731445
OpenAlexW2608519594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.