Evidence map›Paper›PMID 28520851›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

Infectivity of Post-Kala-azar Dermal Leishmaniasis Patients to Sand Flies: Revisiting a Proof of Concept in the Context of the Kala-azar Elimination Program in the Indian Subcontinent.

Ricardo Molina, Debashis Ghosh, Eugenia Carrillo, Séverine Monnerat, Caryn Bern, Dinesh Mondal, Jorge Alvar

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

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  14. Immune response to viscerotropicFrontiers in immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Ricardo MolinaWorld Health Organization Collaborating Centre for Leishmaniasis, Laboratory of Medical Entomology, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
Debashis GhoshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Eugenia CarrilloWorld Health Organization Collaborating Center for Leishmaniasis, Laboratory of Leishmaniasis and Chagas, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
Séverine MonneratDrugs for Neglected Diseases Initiative, Geneva, Switzerland.
Caryn BernDepartment of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco.
Dinesh MondalInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka.
Jorge AlvarDrugs for Neglected Diseases Initiative, Geneva, Switzerland.
Drugs for Neglected Diseases Initiative · CHInstituto de Salud Carlos III · ESInternational Centre for Diarrhoeal Disease Research · BDUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared xenodiagnosis with quantitative polymerase chain reaction in skin biopsies from 3 patients with maculopapular or nodular post-kala-azar dermal leishmaniasis (PKDL). All patients infected sand flies. Parasite loads in skin varied from 1428 to 63 058 parasites per microgram. PKDL detection and treatment are important missing components of the kala-azar elimination program.

Indexed as

Leishmania donovaniLeishmaniasis, VisceralAdultAnimalsDNA, ProtozoanFemaleHumansIndiaMalePolymerase Chain ReactionPsychodidaeSkinXenodiagnosisYoung AdultDNA, Protozoancontrolleishmaniasispost–kala-azar dermal leishmaniasisxenodiagnosis

Identifiers

PMID28520851
PMCPMC5848257
OpenAlexW2614458392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.